We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The interplay between infection risk factors of SARS-CoV-2 and mortality: a cross-sectional study from a cohort of long-term care nursing home residents.
- Authors
Soldevila, Laura; Prat, Núria; Mas, Miquel À.; Massot, Mireia; Miralles, Ramón; Bonet-Simó, Josep M.; Isnard, Mar; Expósito-Izquierdo, Marta; Garcia-Sanchez, Irene; Rodoreda-Noguerola, Sara; Moreno, Nemesio; Badia, Esther; López, Genís; Sevilla, Javier; Estrada, Oriol; Vallès, Xavier
- Abstract
<bold>Background: </bold>Covid-19 pandemic has particularly affected older people living in Long-term Care settings in terms of infection and mortality.<bold>Methods: </bold>We carried out a cross-sectional analysis within a cohort of Long-term care nursing home residents between March first and June thirty, 2020, who were ≥ 65 years old and on whom at least one PCR test was performed. Socio-demographic, comorbidities, and clinical data were recorded. Facility size and community incidence of SARS-CoV-2 were also considered. The outcomes of interest were infection (PCR positive) and death.<bold>Results: </bold>A total of 8021 residents were included from 168 facilities. Mean age was 86.4 years (SD = 7.4). Women represented 74.1%. SARS-CoV-2 infection was detected in 27.7% of participants, and the overall case fatality rate was 11.3% (24.9% among those with a positive PCR test). Epidemiological factors related to risk of infection were larger facility size (pooled aOR 1.73; P < .001), higher community incidence (pooled aOR 1.67, P = .04), leading to a higher risk than the clinical factor of low level of functional dependence (aOR 1.22, P = .03). Epidemiological risk factors associated with mortality were male gender (aOR 1.75; P < .001), age (pooled aOR 1.16; P < .001), and higher community incidence (pooled aOR 1.19, P = < 0.001) whereas clinical factors were low level of functional dependence (aOR 2.42, P < .001), Complex Chronic Condition (aOR 1.29, P < .001) and dementia (aOR 1.33, P <0.001). There was evidence of clustering for facility and health area when considering the risk of infection and mortality (P < .001).<bold>Conclusions: </bold>Our results suggest a complex interplay between structural and individual factors regarding Covid-19 infection and its impact on mortality in nursing-home residents.
- Subjects
NURSING home patients; NURSING home care; MORTALITY risk factors; HEALTH facilities; LONG-term health care; MORTALITY; INFECTION
- Publication
BMC Geriatrics, 2022, Vol 22, Issue 1, p1
- ISSN
1471-2318
- Publication type
journal article
- DOI
10.1186/s12877-022-02779-0