We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Evaluating the ameliorative efficacy of Spirulina platensis on spermatogenesis and steroidogenesis in cadmium-intoxicated rats.
- Authors
Farag, Mayada; Abd EL-Aziz, R.; Ali, H.; Ahmed, Sahar
- Abstract
The present study was conducted to evaluate the ameliorative efficacy of Spirulina platensis (SP) on reproductive dysfunctions induced by cadmium chloride (CdCl) in male rats. Rats ( n = 40) were divided into five groups (eight rats/each). Group 1: served as control without any treatment. Group 2: Rats were administered SP (150 mg/kg body weight (BW)) in drinking water for 10 days. Group3: Rats were subcutaneously injected with CdCl (2 mg/kg BW) daily for 10 days. Group 4: Rats were co-treated with both CdCl (2 mg/kg BW) and SP (150 mg/kg BW) daily for 10 days (SP prophylactic group). Group5: Rats received CdCl for 10 days followed by administration of SP alone in drinking water daily for another 30 days with the same mentioned routes and doses (SP treatment group). From our findings, the administration of SP alone or co-administration with Cd significantly attenuated the harmful effects of Cd, suggesting its beneficial role in improving spermatogenesis and steroidogenesis after Cd exposure.
- Subjects
CADMIUM chloride; SPERMATOGENESIS; SPIRULINA platensis; LABORATORY rats; DRINKING water analysis
- Publication
Environmental Science & Pollution Research, 2016, Vol 23, Issue 3, p2454
- ISSN
0944-1344
- Publication type
Article
- DOI
10.1007/s11356-015-5314-9