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- Title
Concomitant reversible cerebral vasoconstriction syndrome and transient global amnesia.
- Authors
Boitet, Rosalie; Gaillard, Nicolas; Bendiab, Eddine; Corti, Lucas; Roos, Caroline; Reynes, Jacques; Costalat, Vincent; Arquizan, Caroline; Ducros, Anne
- Abstract
Background: Reversible cerebral vasoconstriction syndrome (RCVS) is a common cause of thunderclap headache (TCH), mainly recurrent, sometimes associated with seizures and/or neurological deficit. Association with amnesia is exceptional. We report a case series of RCVS concomitant with transient global amnesia (TGA) and propose pathophysiologic hypotheses. Methods: We retrospectively reviewed clinical and radiological features of patients diagnosed with confirmed concomitant RCVS and TGA between 2012 and 2018 in two specialized institutions. Results: Two women aged 67 and 53, and a 64-year-old man had a first thunderclap headache triggered by an acute emotional stress, rapidly followed by TGA. Amnesia resolved within a few hours and RCVS was proven for all, with complete resolution of vasospasms within 3 months. All three patients had excellent outcome. Conclusions: RCVS and TGA can occur simultaneously, which suggests common mechanisms such as aberrant responses to physical or emotional stress and cerebral vasoconstriction.
- Subjects
VASOCONSTRICTION; AMNESIA; PSYCHOLOGICAL stress; SYNDROMES; TAKOTSUBO cardiomyopathy; SEIZURES (Medicine)
- Publication
Journal of Neurology, 2020, Vol 267, Issue 2, p390
- ISSN
0340-5354
- Publication type
Article
- DOI
10.1007/s00415-019-09594-5