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- Title
Gradient Performance Checks.
- Authors
Gilroy, Jonathan J.; Dolan, John W.
- Abstract
The article presents information on gradient elution. Gradient elution is used widely both in research and production liquid chromatography separations. For routine analyses of drugs in biological matrices, our laboratory prefers to use gradient elution rather than isocratic separations. A built-in cleaning step is part of every gradient method that finishes at a high percentage of strong solvent and gives longer column life with dirty samples. Modern equipment provides a precision and accuracy of gradient control that was not possible with previous generations of equipment.
- Subjects
HIGH performance liquid chromatography; LIQUID chromatography; MATRICES (Mathematics); LABORATORIES; COATING processes; CHROMATOGRAPHIC analysis
- Publication
LC-GC Europe, 2004, Vol 17, Issue 11, p566
- ISSN
1471-6577
- Publication type
Article