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- Title
Studies on cellular mechanism of prion propagation using abnormal isoform prion protein specific detection method.
- Authors
Yamasaki, Takeshi
- Abstract
The article focuses on a study that analyzes the intracellular events that are involved in prion propagation in Transmissible spongiform encephalopathies (TSEs) caused due to the accumulation of prion proteins. It mentions the use of immunofluorescence assay (IFA) for analyzing the events involved in prion propagation. The study reveals that the generation of the isomers of prion protein is associated with neuronal degeneration in the central nervous system in prion diseases.
- Subjects
PRIONS; PRION genetics; CHRONIC wasting disease; PRION diseases; IMMUNOFLUORESCENCE; NEURODEGENERATION
- Publication
Japanese Journal of Veterinary Research, 2013, Vol 61, Issue 1/2, p34
- ISSN
0047-1917
- Publication type
Article