We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Is polycystic ovarian syndrome a risk factor for urolithiasis?
- Authors
Kaygusuz, Ikbal; Karatas, Omer; Kafali, Hasan; Cimentepe, Ersin; Unal, Dogan
- Abstract
Urinary stone disease is a complex multifactorial disorder influenced by both intrinsic and environmental factors. It is generally known that age and sex are risk factors for urinary stone disease. Also men have higher mean urinary oxalate concentrations than women. In addition, in animal and human studies, testosterone has been shown to increase the formation of urinary stones. This suggests that sex hormones are considered to be involved in the pathogenesis of stone disease. Polycystic ovary syndrome (PCOS) is one of the most frequent endocrine disorders of women in the reproductive age, affecting 5-10 % of women in this life span. It is characterized with chronic anovulation\oligo-ovulation, clinical or biochemical evidence of hyperandrogenism and polycystic ovaries on ultrasound examination. Hyperandrogenism, the main feature of PCOS, may trigger the urinary stone formation besides hirsutism, alopecia and acne. Therefore, we hypothesize that PCOS accompanied by hyperandrogenism may be a risk factor in the formation of urinary stone disease.
- Subjects
POLYCYSTIC ovary syndrome; URINARY calculi; MEDICAL imaging systems; KIDNEY stones; HYPERANDROGENISM; PATHOPHYSIOLOGY of androgens
- Publication
Urolithiasis, 2013, Vol 41, Issue 4, p361
- ISSN
2194-7228
- Publication type
Letter
- DOI
10.1007/s00240-013-0564-9