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- Title
Evaluation of nutritional status in patients undergoing hematopoietic SCT.
- Authors
Hadjibabaie, M; Iravani, M; Taghizadeh, M; Ataie-Jafari, A; Shamshiri, A R; Mousavi, S A; Alimoghaddam, K; Hosseini, S; Ghavamzadeh, A
- Abstract
The aims of this study were to establish the nutritional status of patients during hematopoietic SCT (HSCT) and to determine if body mass index (BMI) is a valid indicator of nutritional status in this population when compared with nitrogen balance (NB). In total, 50 patients were enrolled (mean age: 25.7±9.0 years). Patients (14%) were underweight (BMI<18.5 kg/m2), 58% in a normal BMI (between 18.5 and 24.9 kg/m2) and 28% were overweight or obese (BMI25 kg/m2). NB dropped after transplantation and increased from days +5 to +20 after transplantation (P=0.006). There was a significant negative relationship between patients' BMI and time to engraftment (r=−0.45, P=0.001). Engraftment of underweight patients was 3.0 days (P=0.002) and 4.0 days (P<0.001) later than in normal and overweight or obese patients, respectively. There was no significant correlation between NB before transplantation and time to engraftment (r=−0.22, P=0.16). The results of this study demonstrate that patients undergoing HSCT may have suboptimal nutritional status and that pre-HSCT-BMI rather than NB may have a greater correlation in HSCT patients with the time of engraftment. Therefore, it may be useful to consider patient's BMI before transplantation for earlier engraftment time.Bone Marrow Transplantation (2008) 42, 469–473; doi:10.1038/bmt.2008.188; published online 7 July 2008
- Subjects
NUTRITIONAL assessment; BODY mass index; HEMATOPOIETIC stem cells; NITROGEN; BODY weight
- Publication
Bone Marrow Transplantation, 2008, Vol 42, Issue 7, p469
- ISSN
0268-3369
- Publication type
Article
- DOI
10.1038/bmt.2008.188