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- Title
Antihypertensive drug use and cSCC risk.
- Authors
Su, K.A.; Habel, L.A.; Achacoso, N.S.; Friedman, G.D.; Asgari, M.M.
- Abstract
Summary: Over one billion people worldwide have high blood pressure. Many of the medications used to treat high blood pressure are photosensitizing, meaning they make the skin more sensitive to sunlight. As a result, these medications might increase the risk of skin cancer, the most common type of cancer worldwide. This study, from the U.S.A., aimed to find out if people who take blood pressure medications with photosensitizing properties have an increased risk of a certain type of skin cancer called cutaneous squamous cell carcinoma, the second most common type of skin cancer. The researchers identified a group of patients with high blood pressure and looked at what blood pressure medications they took and whether they were ever diagnosed with cutaneous squamous cell carcinoma. The researchers found that patients who take blood pressure medications with photosensitizing properties, including loop diuretics, potassium‐sparing diuretics, and thiazide diuretics, have an increased risk of cutaneous squamous cell carcinoma. The researchers found that the more prescriptions for these medications the patients received, the higher their risk of cutaneous squamous cell carcinoma was. This study suggests that patients taking blood pressure medications with photosensitizing properties may benefit from education on safe sun practices and closer screening for cutaneous squamous cell carcinoma. Linked Article: Su et al. Br J Dermatol 2018; 179:1088–1094
- Subjects
ANTIHYPERTENSIVE agents; RISK factors of skin cancer; HYPERTENSION; PHOTOSENSITIVITY disorders; BLOOD pressure; SQUAMOUS cell carcinoma
- Publication
British Journal of Dermatology, 2018, Vol 179, Issue 5, pe200
- ISSN
0007-0963
- Publication type
Article
- DOI
10.1111/bjd.17211