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- Title
Uspešno lečenje drugog recidiva hepatoblastoma.
- Authors
Krstovski, N.; Radlović, N.; Janić, D.; Dokmanović, L.; Smoljanić, Ž.; Sretenović, A.
- Abstract
Introuduction: The prognosis of hepatoblastoma has changed since effective adjuvant chemotherapy had been introduced in 1980's. There is a general agreement that complete resection is the cornerstone of treatment for children with hepapatoblastorna and the only way for eventual cure. Case report: We describe, a boy with relapsed hepatoblastoma presenting with elevated -fetoprotein (AFP) and no visible tumor by ultrasound and computed tomography (CT). The relapse was treated with chemotherapy. Second relapse occurred shortly after therapy was completed, but this time we waited for tumor mass to appear. Combined surgery and chemotherapy resulted in remission status with 48 months of follow up. Conclusion: Hepatoblastoma relapse without evidence of tumor is not unusual but its treatment remains controversial. Radiological investigations should be repeated until site of relapse is identified. Based on our experience it seems of no benefit to treat isolated elevation of AFP.
- Subjects
TUMORS; DRUG therapy; PHARMACOLOGY; TOMOGRAPHY; MEDICAL radiography; IMMUNOLOGICAL adjuvants
- Publication
Acta Chirurgica Iugoslavica, 2009, Vol 56, Issue 2, p105
- ISSN
0354-950X
- Publication type
Article
- DOI
10.2298/ACI0902105K