We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Synthesis of 2-arylpyridines by the Suzuki–Miyaura cross-coupling of PyFluor with hetero(aryl) boronic acids and esters.
- Authors
Rueda-Espinosa, Juan; Ramanayake, Dewni; Ball, Nicholas D.; Love, Jennifer A.
- Abstract
The Suzuki–Miyaura cross-coupling of pyridine-2-sulfonyl fluoride (PyFluor) with hetero(aryl) boronic acids and pinacol boronic esters is reported. The reactions can be performed using Pd(dppf)Cl2 as the catalyst, at temperatures between 65 and 100 °C and in the presence of water and oxygen. This transformation generates 2-arylpyridines in modest to good yields (5%–89%).
- Subjects
BORONIC acids; BORONIC esters; OXYGEN in water
- Publication
Canadian Journal of Chemistry, 2023, Vol 101, Issue 10, p765
- ISSN
0008-4042
- Publication type
Article
- DOI
10.1139/cjc-2023-0033