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- Title
Safety, feasibility, and effectiveness of implementing supervised exercise into the clinical care of individuals with advanced cancer.
- Authors
Gil Herrero, Lucía; McNeely, Margaret L; Courneya, Kerry S; Castellanos Montealegre, Mónica; González Marquez, Ana Isabel; Pollan Santamaría, Marina; Casla Barrio, Soraya
- Abstract
Objective: To evaluate the safety, feasibility, and preliminary effectiveness of implementing supervised exercise programming into the clinical care of individuals with advanced cancer. Design: Single group implementation feasibility study using a pre–posttest design. Setting: Exercise Oncology Unit of the Spanish Cancer Association (a cancer-specific community facility outside the hospital setting). Participants: Adult individuals with advanced cancer profile involving advanced local cancer or distant metastases. Intervention: A 12-week, twice-weekly, supervised, clinic-based multi-component exercise program. Main Measure: Paired t -tests were used to assess pre–post changes and analyses of covariance were used to compare effects based on selected participant characteristics. Results: Eighty-four individuals with advanced cancer completed the baseline assessment, with six participants withdrawing prior to the start of the program. Of the 78 participants, 17 dropped out, thus, a total of 61 completed the final assessment. Mean adherence was 82.5%. No serious adverse events occurred. Exercise significantly improved VO2max by 5.2 mL·kg·min (p < 0.001), chest strength (p < 0.001), leg strength (p < 0.001), lean body mass (p = 0.003), skeletal muscle mass (p < 0.002), % body fat (p = 0.02), quality of life by 5.3 points (p = 0.009), fatigue by 3.2 points (p = 0.012), and physical activity by 1680 METs/week (p < 0.001). Conclusions: Our clinically supervised and tailored exercise program involving moderate to vigorous intensity exercise was found to be feasible, safe, and effective for individuals with advanced cancer. Implications for Cancer Survivors: With proper screening and supervision, individuals with advanced cancer can benefit from tailored exercise oncology support as part of an overall therapeutic care plan.
- Subjects
SPAIN; PILOT projects; CONFIDENCE intervals; SELF-evaluation; HEALTH outcome assessment; COMMUNITY health services; TUMOR classification; TREATMENT effectiveness; PRE-tests &; post-tests; T-test (Statistics); COMPARATIVE studies; CANCER patients; HUMAN services programs; PHYSICAL activity; ANALYSIS of covariance; DESCRIPTIVE statistics; QUESTIONNAIRES; QUALITY of life; INTEGRATED health care delivery; DATA analysis software; FATIGUE (Physiology); REHABILITATION; CANCER patient rehabilitation; EXERCISE therapy; PATIENT safety; EVALUATION
- Publication
Clinical Rehabilitation, 2022, Vol 36, Issue 12, p1666
- ISSN
0269-2155
- Publication type
Article
- DOI
10.1177/02692155221114556