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- Title
Reply to Natural history of thyroid cancer suggests beginning of the overdiagnosis of juvenile thyroid cancer in the United States and Harm of overdiagnosis or extremely early diagnosis behind trends in pediatric thyroid cancer.
- Authors
Bernier, Marie‐Odile; Kitahara, Cari M.; Shiels, Meredith S.; Bernier, Marie-Odile
- Abstract
Midorikawa et al and Takano expressed concerns about our interpretation and the broader implications of our study, which described trends in pediatric differentiated thyroid cancer incidence rates in the United States between 1998 and 2013.[1] We found that the incidence of differentiated thyroid cancer increased rapidly over the study period for all tumor stages and sizes at the time of diagnosis. However, the large and significant increase in distant differentiated thyroid cancer (ie, disease with extracervical metastases) is incompatible with overdiagnosis being the only factor contributing to the increased incidence of thyroid cancer.
- Subjects
UNITED States; THYROID cancer; CHILDHOOD cancer; OVERDIAGNOSIS; CANCER diagnosis; DISEASE incidence; TRENDS
- Publication
Cancer (0008543X), 2019, Vol 125, Issue 22, p4109
- ISSN
0008-543X
- Publication type
letter
- DOI
10.1002/cncr.32425