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- Title
ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis.
- Authors
Motti, Cherie A.; Ettinger-Epstein, Piers; Willis, Richard H.; Tapiolas, Dianne M.
- Abstract
The viviparous Great Barrier Reef sponge Luffariella variabilis (Poléjaeff 1884) contains a range of secondary metabolites, including manoalide (1) and manoalide monoacetate (3). ESI (+) FTICR-MS accurate mass determination has, for the first time, been used to detected the presence of 3 only in an organic extract of a single L. variabilis larva showing that the parentally produced 3 is sequestered in the larva. As 3 has previously been shown to have antibacterial and quorum sensing inhibition activity, and readily converts to 1, which also exhibits similar activity, it may provide a chemical defence against predation and microbial attack.
- Subjects
LARVAL dispersal; METABOLITES; MARINE metabolites; ANTIBACTERIAL agents; QUORUM sensing; CONTACT inhibition; PREDATOR management; MARINE organisms; CELL communication
- Publication
Marine Drugs, 2010, Vol 8, Issue 1, p190
- ISSN
1660-3397
- Publication type
Article
- DOI
10.3390/md8010190