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- Title
Intravital Microscopy Evidence That Methylene Blue Should Be a Vasopressor-Sparing Agent in Sepsis Vasoplegia.
- Authors
Antunes Cardoso Mestriner, Fabiola Leslie; Brüch Dantas, Pedro; Michelon Barbosa, Jéssyca; Evora, Paulo Roberto B.; Becari, Christiane
- Abstract
Microvasculature failure is expected in sepsis and at higher amine concentrations. Therefore, special attention focused individually on microcirculation is needed. Here, we present that methylene blue can prevent leukocytes from adhering to the endothelium in a rat model of lipopolysaccharide-induced endotoxemia. As hypothesis evidence, an intravital microscopy image is presented.
- Subjects
METHYLENE blue; SEPSIS; MICROSCOPY; ENDOTOXEMIA; ANIMAL disease models
- Publication
Brazilian Journal of Cardiovascular Surgery, 2024, Vol 39, Issue 3, p1
- ISSN
0102-7638
- Publication type
Article
- DOI
10.21470/1678-9741-2023-0066