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- Title
Are Modic changes prognostic for recovery in a cohort of patients with non-specific low back pain?
- Authors
Keller, Anne; Boyle, Eleanor; Skog, Thomas; Cassidy, J.; Bautz-Holter, Erik
- Abstract
Background: There is evidence for an association between Modic type 1 and pain in patients with low back pain (LBP), but little knowledge about its effect on clinical outcomes. Purpose: (1) To assess the prevalence of Modic changes, (2) to determine if Modic changes influence the clinical course of LBP, and (3) to identify prognostic factors for recovery. Study design/setting: Prospective clinical cohort study, with a 1-year follow-up. The treatment consisted of brief intervention and instruction in stretching. Patient's sample: Two hundred and sixty-nine patients with chronic low back pain. Outcome measures: Socio-demographic variables, education, profession, self-reported measures, degenerative changes on MRI. Methods: Linear growth model and Cox regression analysis. Results: Five percent had a normal MRI, 14 and 50% had Modic 1 and Modic 2 changes. Modic changes were not significant covariates for the clinical course of pain, function or fear avoidance beliefs. Education was a strong prognostic factor for recovery. Conclusions: Modic changes did not influence the clinical course of back pain and were not prognostic factors for recovery. Education was strongly associated with recovery.
- Subjects
BACKACHE; COHORT analysis; STRETCH (Physiology); MAGNETIC resonance imaging; REGRESSION analysis; PATIENTS
- Publication
European Spine Journal, 2012, Vol 21, Issue 3, p418
- ISSN
0940-6719
- Publication type
Article
- DOI
10.1007/s00586-011-1964-6