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- Title
Clinical, hematologic, and electrolyte changes with 0.9% sodium chloride or acetated fluids in endurance horses.
- Authors
Fielding, C. Langdon; Gary Magdesian, K.; Meier, Chloe A.; Rhodes, Diane M.
- Abstract
Objective To describe the clinical and laboratory changes associated with the use of IV0.9% sodium chloride and a commercially available acetated fluid ( CAF) to treat endurance horses requiring emergency medical treatment. Design Randomized, controlled clinical trial from 2007 to 2010. Setting Emergency treatment centers of the Western States 100-mile (220 km) endurance ride. Animals Twelve horses requiring emergency medical treatment in the form of IVfluids completed the study. Interventions Horses were assigned to either the 0.9% sodium chloride group (6 horses) or CAF group (6 horses) and received a total of 20 L of fluid. Clinical, hematologic, and electrolyte data were collected prior to and during fluid therapy. Measurements and Main Results As compared to results prior to fluid therapy, horses treated with 0.9% sodium chloride had a decrease in heart rate ( P < 0.01), PCV ( P < 0.001), total plasma protein (TPP) ( P < 0.001), and the sodium-chloride difference ( P < 0.05). These horses also had an increase in plasma chloride ( P < 0.01) and sodium ( P < 0.01) concentrations. Horses treated with CAF showed a decrease in PCV ( P < 0.01) and TPP ( P < 0.001). Conclusions These findings should aid in the design a larger clinical trial to provide further clarification on the effects of type of fluid therapy on clinical and biochemical parameters in endurance horses. The use of 0.9% sodium chloride may not be ideal for the emergency management of endurance horses as it was associated with an increase in plasma chloride concentration.
- Subjects
ENDURANCE horses; SALT; CLINICAL trials; ELECTROLYTE therapy; VETERINARY fluid therapy; VETERINARY emergencies; VETERINARY medicine
- Publication
Journal of Veterinary Emergency & Critical Care, 2012, Vol 22, Issue 3, p327
- ISSN
1479-3261
- Publication type
Article
- DOI
10.1111/j.1476-4431.2012.00745.x