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- Title
Do we need a different organ allocation system for kidney transplants using donors after circulatory death?
- Authors
Benaragama, Shanka K.; Tymkewycz, Teressa; John, Biku J.; Davenport, Andrew; Lindsey, Ben; Nicol, David; Olsburgh, Jonathon; Drage, Martin; Mamode, Nizam; Calder, Francis; Taylor, John; Koffman, Geoff; Kessaris, Nicos; Morsy, Mohamed; Cacciola, Roberto; Puliatti, Carmelo; Fernadez-Diaz, Susana; Syed, Asim; Hakim, Nadey; Papalois, Vassilios
- Abstract
Background There is no national policy for allocation of kidneys from Donation after circulatory death (DCD) donors in the UK. Allocation is geographical and based on individual/regional centre policies. We have evaluated the short term outcomes of paired kidneys from DCD donors subject to this allocation policy. Methods Retrospective analysis of paired renal transplants from DCD's from 2002 to 2010 in London. Cold ischemia time (CIT), recipient risk factors, delayed graft function (DGF), 3 and 12 month creatinine) were compared. Results Complete data was available on 129 paired kidneys.115 pairs were transplanted in the same centre and 14 pairs transplanted in different centres. There was a significant increase in CIT in kidneys transplanted second when both kidneys were accepted by the same centre (15.5 ± 4.1 vs 20.5 ± 5.8 hrs p < 0.0001 and at different centres (15.8 ± 5.3 vs. 25.2 ± 5.5 hrs p = 0.0008). DGF rates were increased in the second implant following sequential transplantation (p = 0.05). Conclusions Paired study sequential transplantation of kidneys from DCD donors results in a significant increase in CIT for the second kidney, with an increased risk of DGF. Sequential transplantation from a DCD donor should be avoided either by the availability of resources to undertake simultaneous procedures or the allocation of kidneys to 2 separate centres.
- Subjects
UNITED Kingdom; ALLOCATION of organs, tissues, etc.; KIDNEY transplantation; ORGAN donors; KIDNEY surgery; GOVERNMENT policy
- Publication
BMC Nephrology, 2014, Vol 15, Issue 1, p1
- ISSN
1471-2369
- Publication type
Article
- DOI
10.1186/1471-2369-15-83