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- Title
Lipid Rescue - Efficacy and Safety Still Unproven.
- Authors
Höjer, Jonas; Jacobsen, Dag; Neuvonen, Pertti J.; Rosenberg, Per H.
- Abstract
The article discusses the beneficial effect of lipid rescue on the toxicity of other drugs. Topics discussed includes safe record maintained by the Intralipid, the soya bean oil-based nutritional lipid emulsion for intravenous administration, pharmaceutical application of stable lipid emulsions as vehicles for various drug such as diazepam, etomidate and propofol, and lack of evidence for positive effects of lipid rescue and its increasingly reported adverse effects.
- Subjects
INTRAVENOUS fat emulsions; PHYSIOLOGICAL effects of lipids; DRUG toxicity; DIAZEPAM; DRUG lipophilicity
- Publication
Basic & Clinical Pharmacology & Toxicology, 2016, Vol 119, Issue 4, p345
- ISSN
1742-7835
- Publication type
Article
- DOI
10.1111/bcpt.12607