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- Title
Mitral Annular Plane Systolic Excursion-Derived Ejection Fraction: A Simple and Valid Tool in Adult Males With Left Ventricular Systolic Dysfunction.
- Authors
Adel, Walaa; Roushdy, Alaa M.; Nabil, Mohamed
- Abstract
Objectives Validation of a mitral annular plane systolic excursion ( MAPSE)-derived formula to calculate the ejection fraction where EF = 4.8 × MAPSE (mm) + 5.8 in adult males with left ventricular ( LV) dysfunction. Background Echocardiographic assessment of LV function generally requires expert echocardiographer and is somewhat subjective and prone to reader discordance. MAPSE has been suggested as a surrogate measurement for LV function. Methods Prospective analysis of 170 male patients with systolic dysfunction by two-dimensional transthoracic echocardiography was carried out. MAPSE and ejection fraction measured by qualitative visual inspection, M-mode, and biplane modified Simpson's rule were measured. MAPSE-derived EF was compared against other conventional methods to measure EF using Bland-Altman analysis and independent t-test. Results There was a significant positive correlation between average MAPSE and EF measured by M-mode (r = 0.554, P < 0.001), Simpson's rule (r = 0.585, P < 0.001), and visual inspection (r = 0.611, P < 0.001). An average MAPSE cutoff value <= 5 provided the best balanced sensitivity (67.1%) and specificity (76.5%) to predict EF < 30%. The mean difference between MAPSE-derived EF and EF measured by visual inspection and by Simpson's method was 3.86 ± 5.24% and 3.57 ± 5.97%, respectively. The least mean difference of 0.5 ± 5.69% was present between MAPSE-derived EF and M-mode-measured EF (P value 0.2). Conclusion MAPSE-derived EF using the equation EF = 4.8 × MAPSE (mm) + 5.8 is a valid technique in adult males with severely impaired LV EF.
- Subjects
EGYPT; HEART ventricle diseases; ALGORITHMS; STATISTICAL correlation; ECHOCARDIOGRAPHY; LEFT heart ventricle; LONGITUDINAL method; RESEARCH methodology; MITRAL valve; SCIENTIFIC observation; T-test (Statistics); RECEIVER operating characteristic curves; DATA analysis software; MEDICAL coding; DESCRIPTIVE statistics; VENTRICULAR ejection fraction
- Publication
Echocardiography, 2016, Vol 33, Issue 2, p179
- ISSN
0742-2822
- Publication type
Article
- DOI
10.1111/echo.13009