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- Title
Targeted Drug Therapies: Beyond Blood Counts and Chemistries.
- Authors
Asfaw, Solomea; Matys, Samantha; Muluneh, Benyam
- Abstract
Although the field of oncology pharmacotherapy has progressed rapidly with the introduction of novel targeted therapies, there are many unintended side effects that require knowledge of laboratory monitoring for appropriate management. The purpose of this article is to summarize the importance of appropriately interpreting laboratory test results, understanding the implications of blood chemistries, and using resources available for monitoring the parameters of novel oncologic therapies. AT A GLANCE * Novel targeted drugs used in cancer treatment can have off-target effects that may affect many organ systems, depending on the drug. * Off-target effects create less predictable side effect profiles compared with cytotoxic chemotherapy. * Nurses can manage treatment side effects through monitoring of laboratory results.
- Subjects
THERAPEUTIC use of antineoplastic agents; IMATINIB -- Therapeutic use; CONTINUING education units; BASAL metabolism; BLOOD testing; BLOOD chemical analysis; CANCER patient medical care; FATIGUE (Physiology); ABDOMINAL pain; ASPARTATE aminotransferase; CHRONIC myeloid leukemia; BILIRUBIN; BLOOD cell count; ROUTINE diagnostic tests; SMALL molecules; IMMUNE checkpoint inhibitors; URINALYSIS; PROGRAMMED cell death 1 receptors; IMATINIB; CANCER fatigue; MUSCLE cramps; PATIENT monitoring; LIVER function tests; PHARMACODYNAMICS
- Publication
Clinical Journal of Oncology Nursing, 2024, Vol 28, Issue 2, p215
- ISSN
1092-1095
- Publication type
Article
- DOI
10.1188/24.CJON.215-219