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- Title
Utility of <sup>99m</sup>Tc-Sestamibi SPECT/CT in the Early Localization of Metastatic Parathyroid Carcinoma.
- Authors
Fernando, Patrick Earl A.; Bautista, Patricia A.
- Abstract
Parathyroid carcinoma is very rare, with only a few documented cases. Hence, metastatic lesions are infrequently documented on scintigraphic imaging. We present a case of a 63-year-old female presenting with elevated serum levels of ionized calcium and parathyroid hormone (PTH) who was referred to our department for a parathyroid scan with SPECT/CT. Parathyroid scintigraphy showed a focus of increased 99mTc-sestamibi uptake corresponding to a solid mass with calcification in the inferior pole of the right thyroid lobe; tracer retention was noted on delayed images. Incidentally, focal uptake was also seen in a soft tissue mass on the 7th right rib. The patient soon underwent total thyroidectomy, with biopsy revealing parathyroid carcinoma on the right lobe. A bone scan done 7 months after surgery confirmed the presence of metastatic bone disease. The concomitant detection of intrathyroidal and extrathyroidal sestamibiavid masses on parathyroid scintigraphy should increase clinical suspicion of a metastatic process from parathyroid carcinoma.
- Subjects
PARATHYROID gland cancer; SINGLE-photon emission computed tomography; PARATHYROID hormone; DIAGNOSIS
- Publication
Asia Oceania Journal of Nuclear Medicine & Biology, 2018, Vol 6, Issue 2, p171
- ISSN
2322-5718
- Publication type
Article
- DOI
10.22038/aojnmb.2017.27484.1190