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- Title
Preconditioned cues have no value.
- Authors
Sharpe, Melissa J.; Batchelor, Hannah M.; Schoenbaum, Geoffrey
- Abstract
Sensory preconditioning has been used to implicate midbrain dopamine in modelbased learning, contradicting the view that dopamine transients reflect model-free value. However, it has been suggested that model-free value might accrue directly to the preconditioned cue through mediated learning. Here, building on previous work (Sadacca et al., 2016), we address this question by testing whether a preconditioned cue will support conditioned reinforcement in rats. We found that while both directly conditioned and second-order conditioned cues supported robust conditioned reinforcement, a preconditioned cue did not. These data show that the preconditioned cue in our procedure does not directly accrue model-free value and further suggest that the cue may not necessarily access value even indirectly in a model-based manner. If so, then phasic response of dopamine neurons to cues in this setting cannot be described as signaling errors in predicting value.
- Subjects
NEURONS; DOPAMINE; LABORATORY animals; MEDIATED learning experience; PREDICTION models
- Publication
eLife, 2017, p1
- ISSN
2050-084X
- Publication type
Article
- DOI
10.7554/eLife.28362