We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Transparency in clinical trials: Adding value to paediatric dental research.
- Authors
Cenci, Maximiliano Sérgio; Franco, Marina Christ; Raggio, Daniela Prócida; Moher, David; Pereira‐Cenci, Tatiana
- Abstract
Background: Even though considered as studies with high methodological power, many RCTs in paediatric dentistry do not have essential quality items in their design, development, and report, making results' reliability questionable, replication challenging to conduct, wasting time, money, and efforts, and even exposing the participants to research for no benefit. Aim: We addressed the main topics related to transparency in clinical research, with an emphasis in paediatric dentistry. Design: We searched for all controlled clinical trials published from January 2019 up to July 2020 in the three paediatric dentistry journals with high journal Impact Factor, indexed on Medline. These papers were assessed for transparency according to Open Science practices and regarding reporting accuracy using some items required by CONSORT. Results: 53.6% of the studies declared registration, 75% had sample size calculation, 98.2% reported randomisation, and from those, 65.4% explained the randomisation method. Besides that, no study shared their data, and 6.8% were published in open access format. Conclusions: Unfortunately, a large proportion of RCTs in paediatric dental research show a lack of transparency and reproducibility.
- Subjects
CLINICAL trials; PEDIATRIC dentistry; DENTAL education; CLINICAL trial registries; ABSTRACTING &; indexing services; BEHAVIOR; CLINICAL medicine research; COMMUNITY health services; DENTAL research; RESEARCH evaluation; STATISTICAL sampling; SAMPLE size (Statistics); ACCESS to information; RANDOMIZED controlled trials; PERIODICAL articles; IMPACT factor (Citation analysis)
- Publication
International Journal of Paediatric Dentistry, 2020, Vol 31, p4
- ISSN
0960-7439
- Publication type
Article
- DOI
10.1111/ipd.12769