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- Title
Polygonum perfoliatum L., an Excellent Herbal Medicine Widely Used in China: A Review.
- Authors
Liu, Junyu; Zeng, Yuanlian; Sun, Guojuan; Yu, Shaopeng; Xu, Yi; He, Chao; Li, Zulun; Jin, Shenrui; Qin, Xuhua
- Abstract
Polygonum perfoliatum L. (synonym: Polygonum knotweed L.; Persicaria perfoliata ; family: Polygonaceae) is a kind of folk traditional Chinese medicine with a long history of wide use in the treatment of ancient internal, surgical, and gynecological diseases. At present, 80 chemical constituents have been isolated from P. perfoliatum , including flavonoids, anthraquinones, terpenoids, phenolic acids, phenylpropanoids, and alkaloids, among which flavonoids are the main active components. Modern studies have shown that P. perfoliatum has pharmacological activities such as anti-inflammatory, anti-bacterial, antiviral, anti-liver fibrosis, antitussive and expectorant, anti-tumor, anti-oxidation, and so on. By consulting and sorting out a large number of related literatures at home and abroad in recent years, this paper systematically reviewed the botany, traditional uses, phytochemistry, pharmacological activities, and quality control of P. perfoliatum , and discussed its development potential in new drug research and clinical application in the future, in order to provide a reference basis for further research and promote the in-depth development and utilization.
- Subjects
CHINA; HERBAL medicine; POLYGONUM; CHINESE medicine; HISTORY of medicine; DRUG development; PHYTOCHEMICALS
- Publication
Frontiers in Pharmacology, 2020, Vol 11, pN.PAG
- ISSN
1663-9812
- Publication type
Article
- DOI
10.3389/fphar.2020.581266