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- Title
Modulators of hypothalamic-pituitary-gonadal axis for the control of spermatogenesis and sperm quality in vertebrates.
- Authors
Meccariello, Rosaria; Fasano, Silvia; Pierantoni, Riccardo; Cobellis, Gilda
- Abstract
This research explores the hypothalamus-pituitary-gonadal (HPG) axis activity for the control of spermatogenesis and quality sperm production. Topics covered include the characteristics of a primitive HPG in hagfish, review articles about the control of fetal and postnatal development of both Leydig and germ cells and the importance of antioxidant defenses, kisspeptins, estradiol, endocannabinoids and gonadotropin-releasing hormone (GnRH).
- Subjects
HYPOTHALAMUS; PITUITARY gland; GONADS; REGULATION of spermatogenesis; SPERMATOZOA; HAGFISHES
- Publication
Frontiers in Endocrinology, 2014, Vol 5, p1
- ISSN
1664-2392
- Publication type
Article
- DOI
10.3389/fendo.2014.00135