We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Delineating Margins of Lentigo Maligna Using a Hyperspectral Imaging System.
- Authors
NEITTAANMÄKI-PERTTU, Noora; GRÖNROOS, Mari; JESKANEN, Leila; PÖLÖNEN, Ilkka; RANKI, Annamari; SAKSELA, Olli; SNELLMAN, Erna
- Abstract
Lentigo maligna (LM) is an in situ form of melanoma which can progress into invasive lentigo maligna melanoma (LMM). Variations in the pigmentation and thus visibility of the tumour make assessment of lesion borders challenging. We tested hyperspectral imaging system (HIS) in in vivo preoperative delineation of LM and LMM margins. We compared lesion margins delineated by HIS with those estimated clinically, and confirmed histologically. A total of 14 LMs and 5 LMMs in 19 patients were included. HIS analysis matched the histopathological analysis in 18/19 (94.7%) cases while in 1/19 (5.3%) cases HIS showed lesion extension not confirmed by histopathology (false positives). Compared to clinical examination, HIS defined lesion borders more accurately in 10/19 (52.6%) of cases (wider, n = 7 or smaller, n = 3) while in 8/19 (42.1%) cases lesion borders were the same as delineated clinically as confirmed histologically. Thus, HIS is useful for the detection of subclinical LM/ LMM borders.
- Subjects
MELANOMA diagnosis; LENTIGO; SKIN tumors; HYPERSPECTRAL imaging systems; IMAGING systems; DIAGNOSIS
- Publication
Acta Dermato-Venereologica, 2015, Vol 95, Issue 5, p549
- ISSN
0001-5555
- Publication type
Article
- DOI
10.2340/00015555-2010