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- Title
Analgesic effectiveness of opioid agonists in post-operative pain after endosseous dental implant placement - A splitmouth randomized control trial.
- Authors
Keerthna, M.; Dhanraj, M.; Jain, Ashish R.
- Abstract
Aim: This study aims to evaluate the analgesic effectiveness of opioid agonists in post-operative pain after endosseous dental implant placements. Materials and Methods: A total of 44 patients requiring the placement of endosseous dental implants were considered in this study for comparing the two drug interventions, namely, the tramadol (opioid analgesic) and aceclofenac administered orally. The identified patients were randomly allocated into two groups, with odd numbers following group A and even numbers following group B and procedure was performed vice versa. Followed by which the procedure was performed and the experimental drug was administered. After a period of 1 week, the implant will be placed on contralateral side and the experimental drug will be administered. The patients graded the pain for both the drugs after 2 hours of dental implant placement with a 100-point visual analog scale. Results: Statistical analysis revealed that according to Mann-Whitney tests performed with this non-parametric population at 5% confidence interval, both the groups showed no statistically significant difference with P = 0.533 retaining the null hypothesis. Conclusion: Both the drugs showed equal effectiveness, and hence, opioid analgesics can be administered in situations where patients are intolerant to non-steroidal anti-inflammatory drugs.
- Subjects
TRAMADOL; POSTOPERATIVE pain; PHYSIOLOGICAL effects of analgesics; ENDOSSEOUS dental implants; RANDOMIZED controlled trials
- Publication
Drug Invention Today, 2018, Vol 10, Issue 2, p121
- ISSN
0975-7619
- Publication type
Article