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- Title
Formulation Consideration of Nanotechnology Based Drug Delivery Systems.
- Authors
Patel, Kaushal P.; Pathak, Chirayu J.; Patel, Rakesh P.
- Abstract
Nanotechnology is the emerging branch of science which attracting increasing attention in the biomedical community, owing to unique prospects for drug delivery. Nanotechnology based formulations have been incorporated in hundreds of different types of products, and the novel properties of nanomaterials offer great promise to provide new technological breakthroughs. The availability of increasingly sophisticated drug formulations and delivery devices has created new opportunities in drug development. However, nanotechnology has potential health and safety risks throughout its product life cycle. The health risk of a nanoparticle is a function of both its hazard to human health and its exposure potential. It is prudent for companies to try to mitigate the potential risks of nanoparticles during the design stage rather than downstream during manufacturing or customer use. By using these design principles, the health risk of the nanoparticle may be mitigated by potentially lowering the hazard and/or the exposure potential of the nanoparticle. The goal of this reviews is to focusing on formulation aspects of nanotechnology which impacts on new drug development. Insoluble drug formulation is one of the chief areas of drug delivery where nanotechnology promises to improve safety and efficacy. However, major hurdles can exist in the design and manufacture of these formulations, such as stability and processing. Large-scale manufacturing and costs of nanomedicines are also important issues to be addressed during formulation development.
- Subjects
NANOTECHNOLOGY; DRUG delivery devices; THERAPEUTIC use of nanostructured materials; DRUG development; MEDICATION safety; PRODUCT life cycle; DRUG design; DRUG side effects
- Publication
Drug Invention Today, 2014, Vol 6, Issue 1, p46
- ISSN
0975-7619
- Publication type
Article