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- Title
Giant angiolymphoid hyperplasia with eosinophilia on the chest.
- Authors
Trindade, Felicidade; Haro, Rosario; Requena, Luis
- Abstract
Angiolymphoid hyperplasia with eosinophilia is a rare vascular proliferation characterized by single or multiple purplish, brownish papules and subcutaneous nodules, sometimes associated with pain or pruritus. This rare benign process occurs with a female predominance. Approximately 85% of the lesions occur in the skin of the head and neck; most of them are around the ear or on the forehead or scalp. Whether angiolymphoid hyperplasia with eosinophilia represents a benign neoplasm or an unusual reaction to varied stimuli, including trauma, the etiology remains unclear. Histopathologically, the lesions consist of a proliferation of blood vessels of variable size lined by large epithelioid endothelial cells and a variable inflammatory infiltrate of lymphocytes and eosinophils, sometimes with lymphoid follicle formation. The lesion is benign but may be persistent and is difficult to eradicate. We report on a case of a 58-year-old Caucasian man who presented a purplish pink dome-shaped tumor of size up to 8 cm in diameter located on the chest. We emphasize this case considering the unusual dimensions of the lesion (8 cm diameter) and the atypical location on the chest.
- Subjects
HYPERPLASIA; EOSINOPHIL disorders; SKIN diseases; TUMOR growth; SKIN blood-vessels; LYMPHOCYTES; CAUCASIAN race
- Publication
Journal of Cutaneous Pathology, 2009, Vol 36, Issue 4, p493
- ISSN
0303-6987
- Publication type
Article
- DOI
10.1111/j.1600-0560.2008.01066.x