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- Title
Free-living wrist and hip accelerometry forecast cognitive decline among older adults without dementia over 1- or 5-years in two distinct observational cohorts.
- Authors
Shi, Chengjian; Babiker, Niser; Urbanek, Jacek K.; Grossman, Robert L.; Huisingh-Scheetz, Megan; Rzhetsky, Andrey
- Abstract
The prevalence of major neurocognitive disorders is expected to rise over the next 3 decades as the number of adults ≥65 years old increases. Noninvasive screening capable of flagging individuals most at risk of subsequent cognitive decline could trigger closer monitoring and preventive strategies. In this study, we used free-living accelerometry data to forecast cognitive decline within 1- or 5-years in older adults without dementia using two cohorts. The first cohort, recruited in the south side of Chicago, wore hip accelerometers for 7 continuous days. The second cohort, nationally recruited, wore wrist accelerometers continuously for 72 h. Separate classifier models forecasted 1-year cognitive decline with over 85% accuracy using hip data and forecasted 5-year cognitive decline with nearly 70% accuracy using wrist data, significant improvements compared to demographics and comorbidities alone. The proposed models are readily translatable to clinical practices serving ageing populations.
- Subjects
TIME; ACCELEROMETRY; DEMENTIA patients; SEX distribution; DEMENTIA; DESCRIPTIVE statistics; COGNITION disorders in old age; LONGITUDINAL method
- Publication
NPJ Aging, 2022, Vol 8, Issue 1, p1
- ISSN
2731-6068
- Publication type
Article
- DOI
10.1038/s41514-022-00087-w