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- Title
Phytochemical composition and antibacterial activity of ethanolic extract from trunk of Rothmannia wittii (Craib) Bremek. (Rubiaceae) newly found in Vietnam.
- Authors
HONG THIEN VAN; TAI THU NGUYEN; HOAI THUONG THI TON; KIM TRUC THI DINH; VAN SON LE; TAN VIET PHAM; GIA BUU TRAN
- Abstract
Rothmannia wittii, which is found in Binh Chau-Phuoc Buu Nature Reserve, Bung Rieng ward, Xuyen Moc District, Ba Ria-Vung Tau Province, Vietnam, is a rare species of Rubiaceae family. The present study aimed to determine the phytochemical composition and antimicrobial activity of the ethanolic extract of the R. wittii trunk. A total of 10 compounds were identified by liquid chromatography-mass spectrophotometry (LC-MS), including 1) benzene, 1-(1,5-dimethyl-4-hexenyl)-4-methyl, 2) diphenylsulfone, 3) 6ß-hydroxy-10-O-acetylgenipin, 4) cinnamyl-cinnamate, 5) genipin, 6) megastigmatrienone, 7) ethyl p-methoxy-trans-cinnamate, 8) rothalazepane, 9) 1,3,6-trimethylpyrano[2,3-d ]imidazole-2,5(1H,3H)-dione, and 10) shanzhiol. The extract also exhibited an antibacterial activity against six bacterial strains: Bacillus cereus, Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Salmonella typhimurium and Salmonella enteritidis, as determined via disk diffusion agar method.
- Subjects
VIETNAM; RUBIACEAE; SALMONELLA enteritidis; ENDANGERED species; BACILLUS cereus; NATURE reserves; SALMONELLA typhimurium
- Publication
Biotechnologia, 2020, Vol 101, Issue 4, p301
- ISSN
0860-7796
- Publication type
Article
- DOI
10.5114/bta.2020.100422