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- Title
Study to determine the regenerative activity of tincture of Hamamelis virginiana L. (Hamamelidaceae), Maytenus ilicifolia Mart. ex Reissek (Celastraceae) and Casearia sylvestris Sw. (Salicaceae) in an experimental model using Escherichia coli cultures.
- Authors
Primon, Evelise Camila; da Rocha, Susana Beatriz; Bonilha Dezena, Renan Marcel; da Silva, Gustavo Henrique
- Abstract
Introduction: The induction of bacterial growth, in the experimental design used, was proposed as a strategy for evaluating the regeneration of epithelial tissue through the production of extracellular matrix by the fibroblast, collaborating with the healing process, in addition to inducing the production of glycocalyx in epithelial cells, facilitating adhesion and migration to recover the injured region. Aim: To determine the action of the tinctures of Hamamelis virginiana, Maytenus ilicifolia and Casearia sylvestris on the growth of Escherichia coli cultures, to simulate, in this type of model, the potential regenerative activity of connective and epithelial cells, especially the fibroblast, by means of the disk-diffusion and spectrophotometric. Results: The tinctures of Hamamelis virginiana, Maytenus ilicifolia and Casearia sylvestris at high and medium concentrations (above 1.6%) inhibit the development of Escherichia coli in culture, but at low concentrations (from 0.4 to 1.6%) induce bacterial proliferation, especially in the case of Maytenus ilicifolia and Casearia sylvestris tinctures.
- Subjects
GLYCOCALYX; ESCHERICHIA coli; MAYTENUS; REGENERATION (Biology); CELASTRACEAE; SALICACEAE
- Publication
Revista Colombiana de Ciencias Químico-Farmacéuticas, 2023, Vol 52, Issue 2, p826
- ISSN
0034-7418
- Publication type
Article
- DOI
10.15446/rcciquifa.v52n2.110744