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Reovirus intermediate subviral particles constitute a strategy to infect intestinal epithelial cells by exploiting TGF-β dependent pro-survival signaling.
Published in:
Cellular Microbiology, 2016, v. 18, n. 12, p. 1831, doi. 10.1111/cmi.12626
By:
- Stanifer, Megan L.;
- Rippert, Anja;
- Kazakov, Alexander;
- Willemsen, Joschka;
- Bucher, Delia;
- Bender, Silke;
- Bartenschlager, Ralf;
- Binder, Marco;
- Boulant, Steeve
Publication type:
Article
The Interferon Response Dampens the Usutu Virus Infection-Associated Increase in Glycolysis.
Published in:
Frontiers in Cellular & Infection Microbiology, 2022, v. 11, p. 1, doi. 10.3389/fcimb.2022.823181
By:
- Wald, Maria Elisabeth;
- Sieg, Michael;
- Schilling, Erik;
- Binder, Marco;
- Vahlenkamp, Thomas Wilhelm;
- Claus, Claudia
Publication type:
Article
Robust RNAi enhancement via human Argonaute-2 overexpression from plasmids, viral vectors and cell lines.
Published in:
Nucleic Acids Research, 2013, v. 41, n. 21, p. e199, doi. 10.1093/nar/gkt836
By:
- Börner, Kathleen;
- Niopek, Dominik;
- Cotugno, Gabriella;
- Kaldenbach, Michaela;
- Pankert, Teresa;
- Willemsen, Joschka;
- Zhang, Xian;
- Schürmann, Nina;
- Mockenhaupt, Stefan;
- Serva, Andrius;
- Hiet, Marie-Sophie;
- Wiedtke, Ellen;
- Castoldi, Mirco;
- Starkuviene, Vytaute;
- Erfle, Holger;
- Gilbert, Daniel F.;
- Bartenschlager, Ralf;
- Boutros, Michael;
- Binder, Marco;
- Streetz, Konrad
Publication type:
Article
NUDT2 initiates viral RNA degradation by removal of 5′-phosphates.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27239-y
By:
- Laudenbach, Beatrice T.;
- Krey, Karsten;
- Emslander, Quirin;
- Andersen, Line Lykke;
- Reim, Alexander;
- Scaturro, Pietro;
- Mundigl, Sarah;
- Dächert, Christopher;
- Manske, Katrin;
- Moser, Markus;
- Ludwig, Janos;
- Wohlleber, Dirk;
- Kröger, Andrea;
- Binder, Marco;
- Pichlmair, Andreas
Publication type:
Article
Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19.
Published in:
Nature Biotechnology, 2021, v. 39, n. 6, p. 705, doi. 10.1038/s41587-020-00796-1
By:
- Trump, Saskia;
- Lukassen, Soeren;
- Anker, Markus S.;
- Chua, Robert Lorenz;
- Liebig, Johannes;
- Thürmann, Loreen;
- Corman, Victor Max;
- Binder, Marco;
- Loske, Jennifer;
- Klasa, Christina;
- Krieger, Teresa;
- Hennig, Bianca P.;
- Messingschlager, Marey;
- Pott, Fabian;
- Kazmierski, Julia;
- Twardziok, Sven;
- Albrecht, Jan Philipp;
- Eils, Jürgen;
- Hadzibegovic, Sara;
- Lena, Alessia
Publication type:
Article
Phosphorylation of TRIM28 Enhances the Expression of IFN-β and Proinflammatory Cytokines During HPAIV Infection of Human Lung Epithelial Cells.
Published in:
Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02229
By:
- Krischuns, Tim;
- Günl, Franziska;
- Henschel, Lea;
- Binder, Marco;
- Willemsen, Joschka;
- Schloer, Sebastian;
- Rescher, Ursula;
- Gerlt, Vanessa;
- Zimmer, Gert;
- Nordhoff, Carolin;
- Ludwig, Stephan;
- Brunotte, Linda
Publication type:
Article
Immune–epithelial cell cross‐talk enhances antiviral responsiveness to SARS‐CoV‐2 in children.
Published in:
EMBO Reports, 2023, v. 24, n. 12, p. 1, doi. 10.15252/embr.202357912
By:
- Magalhães, Vladimir G;
- Lukassen, Sören;
- Drechsler, Maike;
- Loske, Jennifer;
- Burkart, Sandy S;
- Wüst, Sandra;
- Jacobsen, Eva‐Maria;
- Röhmel, Jobst;
- Mall, Marcus A;
- Debatin, Klaus‐Michael;
- Eils, Roland;
- Autenrieth, Stella;
- Janda, Aleš;
- Lehmann, Irina;
- Binder, Marco
Publication type:
Article
High-resolution kinetic characterization of the RIG-I-signaling pathway and the antiviral response.
Published in:
Life Science Alliance, 2023, v. 6, n. 10, p. 1, doi. 10.26508/lsa.202302059
By:
- Burkart, Sandy S.;
- Schweinoch, Darius;
- Frankish, Jamie;
- Sparn, Carola;
- Wüst, Sandra;
- Urban, Christian;
- Merlo, Marta;
- Magalhães, Vladimir G.;
- Piras, Antonio;
- Pichlmair, Andreas;
- Willemsen, Joschka;
- Kaderali, Lars;
- Binder, Marco
Publication type:
Article
Cellular ROS tolerance determines the effect of plumbagin on osteoclast differentiation.
Published in:
FASEB Journal, 2023, v. 37, n. 12, p. 1, doi. 10.1096/fj.202301415R
By:
- Sultanli, Sevinj;
- Schneider, Jakob;
- Burkart, Sandy S.;
- Binder, Marco;
- Kubatzky, Katharina F.
Publication type:
Article
Hepatitis C: A mouse at the end of the tunnel.
Published in:
Cell Research, 2013, v. 23, n. 12, p. 1343, doi. 10.1038/cr.2013.132
By:
- Binder, Marco;
- Bartenschlager, Ralf
Publication type:
Article
Disentangling molecular mechanisms regulating sensitization of interferon alpha signal transduction.
Published in:
Molecular Systems Biology, 2020, v. 16, n. 7, p. 1, doi. 10.15252/msb.20198955
By:
- Kok, Frédérique;
- Rosenblatt, Marcus;
- Teusel, Melissa;
- Nizharadze, Tamar;
- Gonçalves Magalhães, Vladimir;
- Dächert, Christopher;
- Maiwald, Tim;
- Vlasov, Artyom;
- Wäsch, Marvin;
- Tyufekchieva, Silvana;
- Hoffmann, Katrin;
- Damm, Georg;
- Seehofer, Daniel;
- Boettler, Tobias;
- Binder, Marco;
- Timmer, Jens;
- Schilling, Marcel;
- Klingmüller, Ursula
Publication type:
Article
Influenza A virus strain PR/8/34, but neither HAM/2009 nor WSN/33, is transiently inhibited by the PB2-targeting drug paliperidone.
Published in:
Archives of Virology, 2023, v. 168, n. 2, p. 1, doi. 10.1007/s00705-022-05696-0
By:
- Panagiotidis, Georgios-Dimitrios;
- Müller, Christin;
- Binder, Marco;
- Weber, Friedemann
Publication type:
Article
Persistent Innate Immune Stimulation Results in IRF3-Mediated but Caspase-Independent Cytostasis.
Published in:
Viruses (1999-4915), 2020, v. 12, n. 6, p. 635, doi. 10.3390/v12060635
By:
- Urban, Christian;
- Welsch, Hendrik;
- Heine, Katharina;
- Wüst, Sandra;
- Haas, Darya A.;
- Dächert, Christopher;
- Pandey, Aparna;
- Pichlmair, Andreas;
- Binder, Marco
Publication type:
Article
Gene Expression Profiling of Different Huh7 Variants Reveals Novel Hepatitis C Virus Host Factors.
Published in:
Viruses (1999-4915), 2020, v. 12, n. 1, p. 36, doi. 10.3390/v12010036
By:
- Dächert, Christopher;
- Gladilin, Evgeny;
- Binder, Marco
Publication type:
Article
Activation of Type I and III Interferon Response by Mitochondrial and Peroxisomal MAVS and Inhibition by Hepatitis C Virus.
Published in:
PLoS Pathogens, 2015, v. 11, n. 11, p. 1, doi. 10.1371/journal.ppat.1005264
By:
- Bender, Silke;
- Reuter, Antje;
- Eberle, Florian;
- Einhorn, Evelyne;
- Binder, Marco;
- Bartenschlager, Ralf
Publication type:
Article
Replication Vesicles are Load- and Choke-Points in the Hepatitis C Virus Lifecycle.
Published in:
PLoS Pathogens, 2013, v. 9, n. 8, p. 1, doi. 10.1371/journal.ppat.1003561
By:
- Binder, Marco;
- Sulaimanov, Nurgazy;
- Clausznitzer, Diana;
- Schulze, Manuel;
- Hüber, Christian M.;
- Lenz, Simon M.;
- Schlöder, Johannes P.;
- Trippler, Martin;
- Bartenschlager, Ralf;
- Lohmann, Volker;
- Kaderali, Lars
Publication type:
Article
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus.
Published in:
Nature, 2005, v. 437, n. 7062, p. 1167, doi. 10.1038/nature04193
By:
- Meylan, Etienne;
- Curran, Joseph;
- Hofmann, Kay;
- Moradpour, Darius;
- Binder, Marco;
- Bartenschlager, Ralf;
- Tschopp, Jürg
Publication type:
Article
Mathematical modeling of plus-strand RNA virus replication to identify broad-spectrum antiviral treatment strategies.
Published in:
PLoS Computational Biology, 2023, v. 19, n. 4, p. 1, doi. 10.1371/journal.pcbi.1010423
By:
- Zitzmann, Carolin;
- Dächert, Christopher;
- Schmid, Bianca;
- van der Schaar, Hilde;
- van Hemert, Martijn;
- Perelson, Alan S.;
- van Kuppeveld, Frank J. M.;
- Bartenschlager, Ralf;
- Binder, Marco;
- Kaderali, Lars
Publication type:
Article
Viral immune modulators perturb the human molecular network by common and unique strategies.
Published in:
Nature, 2012, v. 487, n. 7408, p. 486, doi. 10.1038/nature11289
By:
- Pichlmair, Andreas;
- Kandasamy, Kumaran;
- Alvisi, Gualtiero;
- Mulhern, Orla;
- Sacco, Roberto;
- Habjan, Matthias;
- Binder, Marco;
- Stefanovic, Adrijana;
- Eberle, Carol-Ann;
- Goncalves, Adriana;
- Bürckstümmer, Tilmann;
- Müller, André C.;
- Fauster, Astrid;
- Holze, Cathleen;
- Lindsten, Kristina;
- Goodbourn, Stephen;
- Kochs, Georg;
- Weber, Friedemann;
- Bartenschlager, Ralf;
- Bowie, Andrew G.
Publication type:
Article
RIPLET, and not TRIM25, is required for endogenous RIG‐I‐dependent antiviral responses.
Published in:
Immunology & Cell Biology, 2019, v. 97, n. 9, p. 840, doi. 10.1111/imcb.12284
By:
- Hayman, Thomas J;
- Hsu, Alan C;
- Kolesnik, Tatiana B;
- Dagley, Laura F;
- Willemsen, Joschka;
- Tate, Michelle D;
- Baker, Paul J;
- Kershaw, Nadia J;
- Kedzierski, Lukasz;
- Webb, Andrew I;
- Wark, Peter A;
- Kedzierska, Katherine;
- Masters, Seth L;
- Belz, Gabrielle T;
- Binder, Marco;
- Hansbro, Philip M;
- Nicola, Nicos A;
- Nicholson, Sandra E
Publication type:
Article
Comparative Analysis of Six IRF Family Members in Alveolar Epithelial Cell-Intrinsic Antiviral Responses.
Published in:
Cells (2073-4409), 2021, v. 10, n. 10, p. 2600, doi. 10.3390/cells10102600
By:
- Wüst, Sandra;
- Schad, Paulina;
- Burkart, Sandy;
- Binder, Marco
Publication type:
Article
Hepatitis C virus targets the interferon-α JAK/STAT pathway by promoting proteasomal degradation in immune cells and hepatocytes.
Published in:
FEBS Letters, 2013, v. 587, n. 10, p. 1571, doi. 10.1016/j.febslet.2013.03.041
By:
- Stevenson, Nigel J.;
- Bourke, Nollaig M.;
- Ryan, Elizabeth J.;
- Binder, Marco;
- Fanning, Liam;
- Johnston, James A.;
- Hegarty, John E.;
- Long, Aideen;
- O’Farrelly, Cliona
Publication type:
Article
Tumour cells can escape antiproliferative pressure by interferon-β through immunoediting of interferon receptor expression.
Published in:
Cancer Cell International, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12935-023-03150-y
By:
- Hiebinger, Felix;
- Kudulyte, Aiste;
- Chi, Huanting;
- Burbano De Lara, Sebastian;
- Ilic, Doroteja;
- Helm, Barbara;
- Welsch, Hendrik;
- Dao Thi, Viet Loan;
- Klingmüller, Ursula;
- Binder, Marco
Publication type:
Article
Tumour cells can escape antiproliferative pressure by interferon-β through immunoediting of interferon receptor expression.
Published in:
Cancer Cell International, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12935-023-03150-y
By:
- Hiebinger, Felix;
- Kudulyte, Aiste;
- Chi, Huanting;
- Burbano De Lara, Sebastian;
- Ilic, Doroteja;
- Helm, Barbara;
- Welsch, Hendrik;
- Dao Thi, Viet Loan;
- Klingmüller, Ursula;
- Binder, Marco
Publication type:
Article
Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses.
Published in:
PLoS Pathogens, 2020, v. 16, n. 10, p. 1, doi. 10.1371/journal.ppat.1008461
By:
- Robichon, Katharina;
- Maiwald, Tim;
- Schilling, Marcel;
- Schneider, Annette;
- Willemsen, Joschka;
- Salopiata, Florian;
- Teusel, Melissa;
- Kreutz, Clemens;
- Ehlting, Christian;
- Huang, Jun;
- Chakraborty, Sajib;
- Huang, Xiaoyun;
- Damm, Georg;
- Seehofer, Daniel;
- Lang, Philipp A.;
- Bode, Johannes G.;
- Binder, Marco;
- Bartenschlager, Ralf;
- Timmer, Jens;
- Klingmüller, Ursula
Publication type:
Article
Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation.
Published in:
PLoS Computational Biology, 2020, v. 16, n. 2, p. 1, doi. 10.1371/journal.pcbi.1007587
By:
- Dirmeier, Simon;
- Dächert, Christopher;
- van Hemert, Martijn;
- Tas, Ali;
- Ogando, Natacha S.;
- van Kuppeveld, Frank;
- Bartenschlager, Ralf;
- Kaderali, Lars;
- Binder, Marco;
- Beerenwinkel, Niko
Publication type:
Article
A Coupled Mathematical Model of the Intracellular Replication of Dengue Virus and the Host Cell Immune Response to Infection.
Published in:
Frontiers in Microbiology, 2020, v. 11, p. 1, doi. 10.3389/fmicb.2020.00725
By:
- Zitzmann, Carolin;
- Schmid, Bianca;
- Ruggieri, Alessia;
- Perelson, Alan S.;
- Binder, Marco;
- Bartenschlager, Ralf;
- Kaderali, Lars
Publication type:
Article
Bacterial RNA is recognized by different sets of immunoreceptors.
Published in:
European Journal of Immunology, 2009, v. 39, n. 9, p. 2537, doi. 10.1002/eji.200838978
By:
- Eberle, Florian;
- Sirin, Mehtap;
- Binder, Marco;
- Dalpke, Alexander H.
Publication type:
Article

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