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- Title
Effect of Initial Therapy on TGF-β1 Protein Levels in Gingival Crevicular Fluid (GCF) of Chronic Gingivitis Patients.
- Authors
Astuti, Lilies Anggarwati; Hatta, Mochammad; Rubianto, Mochammad; Oktawati, Sri; Tahir, Hasanuddin
- Abstract
Gingivitis is a process of inflammation of the periodontal tissue which is confined to the gingiva characterized by hiperemi, swelling, tendency to bleeding in the gingiva. Local causes include plaque deposits and calculus. initial therapy aims to prevent more severe periodontal inflammation. Research purposes to determine the effect of initial therapy on TGF-β1 protein levels in GCF in patients with chronic gingivitis. The type of research was observational analytic on TGF- β1 protein levels in chronic gingivitis patients, carried out on 10 samples that were controlled 2 times after initial treatment in the form of scaling and root planning in patients with chronic gingivitis. Research Result: The average level of TGF- β1 protein during pre-therapy was 1081.55 pg/ml, when observation 1 decreased by 599.67 pg/ml and when the second observation increased 957.12 pg/ml, the results of the paired T test obtained a value of p < 0.05. Conclusion: Decreased levels of TGF- β1 protein in GCF of chronic gingivitis patients after initial therapy for severe gingivitis.
- Subjects
GINGIVITIS; GINGIVAL fluid; PROTEINS
- Publication
Indian Journal of Public Health Research & Development, 2020, Vol 11, Issue 4, p720
- ISSN
0976-0245
- Publication type
Article