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- Title
Fatigue Is Associated with Poor Sleep in People with Multiple Sclerosis and Cognitive Impairment.
- Authors
Cameron, Michelle H.; Peterson, Vanessa; Boudreau, Eilis A.; Downs, Ashley; Lovera, Jesus; Kim, Edward; McMillan, Garnett P.; Turner, Aaron P.; Haselkorn, Jodie K.; Bourdette, Dennis
- Abstract
Background. Fatigue is the most common symptom in people with multiple sclerosis (MS). Poor sleep also occurs in this population. Objective. The objective of this study was to determine the relationship between fatigue and sleep quality in people with MS and cognitive impairment. Method. This cross-sectional study assessed relationships among fatigue, assessed with the Modified Fatigue Impact Scale (MFIS) and the Fatigue Severity Scale (FSS), sleep quality assessed with the Pittsburg Sleep Quality Index (PSQI), and demographics in 121 people with MS and cognitive impairment. Results. Fatigue was significantly correlated with poor sleep quality (MFIS: F = 15.60, P < 0.01; FSS: F = 12.09, P < 0.01). FSS scores were also significantly correlated with the PSQI subscore for daytime dysfunction and MFIS scores were significantly correlated with disability, age, and the PSQI subscores for sleep quality, sleep duration, and daytime dysfunction. Conclusions. This study demonstrates a relationship between fatigue and sleep quality in individuals with MS and cognitive impairment.
- Subjects
SLEEP; MULTIPLE sclerosis; MYELIN sheath diseases; MILD cognitive impairment; COGNITION disorders
- Publication
International Journal of Medicinal Chemistry, 2014, p1
- ISSN
2090-2069
- Publication type
Article
- DOI
10.1155/2014/872732