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- Title
From Inflammation to Current and Alternative Therapies Involved in Wound Healing.
- Authors
Serra, Mariana Barreto; Barroso, Wermerson Assunção; Silva, Neemias Neves da; Silva, Selma do Nascimento; Borges, Antonio Carlos Romão; Abreu, Iracelle Carvalho; Borges, Marilene Oliveira da Rocha
- Abstract
Wound healing is a complex event that develops in three overlapping phases: inflammatory, proliferative, and remodeling. These phases are distinct in function and histological characteristics. However, they depend on the interaction of cytokines, growth factors, chemokines, and chemical mediators from cells to perform regulatory events. In this article, we will review the pathway in the skin healing cascade, relating the major chemical inflammatory mediators, cellular and molecular, as well as demonstrating the local and systemic factors that interfere in healing and disorders associated with tissue repair deficiency. Finally, we will discuss the current therapeutic interventions in the wounds treatment, and the alternative therapies used as promising results in the development of new products with healing potential.
- Publication
International Journal of Inflammation, 2017, p1
- ISSN
2090-8040
- Publication type
Article
- DOI
10.1155/2017/3406215