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- Title
Expression of human protein S100A7 (psoriasin), preparation of antibody and application to human larynx squamous cell carcinoma.
- Abstract
The article offers information on the study conducted by the authors related to the expression of human protein S100A7 (psoriasin), preparation of antibody and application to human larynx squamous cell carcinoma. It states up-regulation of S100A7 (Psoriasin), a small calcium-binding protein, is associated with the development of several types of carcinomas, but its function and possibility to serve as a diagnostic or prognostic marker have not been fully defined. It mentions that in order to prepare antibodies to the protein for immunohistochemical studies we produced the recombinant S100A7 protein in E. coli. Messenger RNA (mRNA) extracted from human tracheal tumor tissue was amplified by RT-PCR to provide the region coding for the S100A7 gene.
- Publication
BMC Research Notes, 2011, Vol 4, Issue 1, p494
- ISSN
1756-0500
- Publication type
Article
- DOI
10.1186/1756-0500-4-494