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- Title
Assessment of the accuracy and precision of the i-Smart 30 VET Electrolyte Analyzer in dogs, cats, cattle and pigs.
- Authors
Kim, Han‐Jun; Lee, Hye‐Rim; Park, Yoon‐Seo; Kyung, Soon‐Goo; Do, Sun Hee
- Abstract
Background Performance evaluation of point-of-care ( POC) electrolyte analyzers is essential for determining their precision and accuracy in clinical practice. Objective The purpose of this study was to validate the i-Smart 30 VET Electrolyte Analyzer for canine, feline, bovine, and porcine samples in comparison with the ion-selective electrolyte analyzer Roche 9180 electrolyte analyzer. Methods A total of 400 heparinized whole blood samples were collected and analyzed by both instruments for sodium, potassium, and chloride concentrations. Within-run, between-day, and total imprecision were evaluated. Statistical analyses included tests for correlation, regression, bias, and total error. Results The coefficients of variation ( CV) of both within-run and between-day imprecisions in the i-Smart 30 VET ranged from 0.4-1.6%. In addition, total CV (0.3-1.7%) and total error (0.7-3.7%) of the i-Smart 30 VET were acceptable according to the ASVCP guidelines (< 5%). The correlation between the i-Smart 30 VET and the Roche 9180 was excellent ( r > .98). There was no proportional error according to the regression (slope ranges 0.92-1.00, 95% CI includes 1.00), but a constant error was detected for sodium concentration in dogs (interval = 0.5), cattle (interval = 3.0), and pigs (interval = 4.0), and for chloride concentration in cats (interval = 1.0). Most of the bias was within 95% CI, and the total error range (0.8-3.5%) was acceptable according to ASVCP guidelines. Conclusion The i-Smart 30 VET Electrolyte Analyzer provides precise and accurate measurements of sodium, potassium, and chloride concentrations in whole blood samples from dogs, cats, cattle, and pigs.
- Subjects
CHLORIDES; POINT-of-care testing; POTASSIUM; SODIUM; CATTLE; STATISTICAL correlation
- Publication
Veterinary Clinical Pathology, 2015, Vol 44, Issue 3, p410
- ISSN
0275-6382
- Publication type
Article
- DOI
10.1111/vcp.12267