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- Title
CAR-T cell therapy seeks strategies to harness cytokine storm.
- Authors
DeFrancesco, Laura
- Abstract
The article focuses on the attempt made by the researcher Crystal Mackall and colleagues for the treatment of cancer by the immunotherapy chimeric antigen receptors T(CAR-T). Topics discussed include release of toxic levels of cytokines, symptoms of antibody therapeutics includes mild nausea, fever and multiple organ failure and reduction in the timing of induction of chemotherapy. It mentions the development of cytokine release syndrome after the toxic release of cytokines.
- Subjects
MACKALL, Crystal; CANCER treatment; MULTIPLE organ failure; CYTOKINES; CANCER chemotherapy
- Publication
Nature Biotechnology, 2014, Vol 32, Issue 7, p604
- ISSN
1087-0156
- Publication type
Article
- DOI
10.1038/nbt0714-604