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- Title
Association between urinary tract infection, renal damage and birth size.
- Authors
Hellström, M; Hessel, H; Jacobsson, B; Jodal, U; Niklasson, A; Wennerström, M; Hellström, A
- Abstract
The aim of this study was to investigate whether birth size is associated with permanent renal damage in children with urinary tract infection (UTI). A cohort of 1221 children under 16 y of age was diagnosed with their first symptomatic UTI between 1970 and 1979. Of these, 74 had urographic renal scarring in childhood and 57 were re-examined as adults. The birth files of 48 of these patients (35F, 13M) were available, and birthweight and birthlength in relation to gestational age were analysed and compared with a Swedish reference population. Children who had renal damage without vesicoureteric reflux were significantly smaller at birth (median weight,-0.76 SDS) compared with both children who had renal damage and reflux (median weight,-0.01 SDS) and the reference population. Conclusion: The demonstration of low birthweight among children with UTI and renal damage but no reflux suggests that low birthweight may be a risk factor for the development of renal damage.
- Subjects
SWEDEN; URINARY tract infections; BIRTH weight; JUVENILE diseases; DISEASE risk factors
- Publication
Acta Paediatrica, 2001, Vol 90, Issue 6, p628
- ISSN
0803-5253
- Publication type
Article
- DOI
10.1111/j.1651-2227.2001.tb02424.x