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- Title
Approximate entropy as a measure of irregularity for psychiatric serial metrics.
- Authors
Pincus, Steven M
- Abstract
Objectives: The quantification of subtle patterns in sequential data, and their changes, has considerable potential utility throughout psychiatry, including the analyses of mood ratings, heart rate, respiratory, and electroencephalographic recordings. Methods: Approximate entropy (ApEn), a relatively recently developed statistic quantifying serial irregularity, has been applied in numerous studies throughout mathematics and other fields of study, especially biology. Results: We discussed applications of ApEn, both extant and potential, of most relevance to psychiatrists. We provided a mechanistic interpretation of lowered ApEn values, and discusses the relationship between ApEn and other (both classical and complexity) measures of serial dynamics. We also briefly discussed cross-ApEn, a thematically similar quantification of two-variable asynchrony that can aid in uncovering subtle disruptions in complicated network dynamics. Conclusions: ApEn and cross-ApEn have significant potential to consequentially enhance present statistical methodologies of analysis of psychiatric data, in both clinical and in research settings.
- Subjects
BIPOLAR disorder; AFFECTIVE disorders; ENTROPY; BEHAVIORAL &; Emotional Rating Scale; MEDICAL care of people with mental illness; RANDOM walks
- Publication
Bipolar Disorders, 2006, Vol 8, Issue 5, p430
- ISSN
1398-5647
- Publication type
Article
- DOI
10.1111/j.1399-5618.2006.00375.x