We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Correction: A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.
- Authors
Emdin, Connor A.; Haas, Mary E.; Khera, Amit V.; Aragam, Krishna; Chaffin, Mark; Klarin, Derek; Hindy, George; Jiang, Lan; Wei, Wei-Qi; Feng, Qiping; Karjalainen, Juha; Havulinna, Aki; Kiiskinen, Tuomo; Bick, Alexander; Ardissino, Diego; Wilson, James G.; Schunkert, Heribert; McPherson, Ruth; Watkins, Hugh; Elosua, Roberto
- Abstract
(PDF) Reference 1 Emdin CA, Haas ME, Khera AV, Aragam K, Chaffin M, Klarin D, et al. (2020) A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease. In the Methods, the first sentence of the first paragraph: To examine whether known alcoholic and non-alcoholic cirrhosis variants associate with all-cause cirrhosis, we tested the association of six known cirrhosis variants ( I PNPLA3 i I48M, I TM6SF2 i E167K, I MBOAT7 i rs641738, I HSD17B13 i rs72613567, I HFE i C282Y and I SERPINA1 i E366K [11,16,18,19]) with all-cause cirrhosis in UK Biobank (hospitalization or death due to ICD codes K70.2, K70.3, K70.4, K74.0, K74.1, K74.2, K74.6, K76.6, or I85). should read: To examine whether known alcoholic and non-alcoholic cirrhosis variants associate with all-cause cirrhosis, we tested the association of six known cirrhosis variants ( I PNPLA3 i I148M, I TM6SF2 i E167K, I MBOAT7 i rs641738, I HSD17B13 i rs72613567, I HFE i C282Y and I SERPINA1 i E366K [11,16,18,19]) with all-cause cirrhosis in UK Biobank (hospitalization or death due to ICD codes K70.2, K70.3, K70.4, K74.0, K74.1, K74.2, K74.6, K76.6, or I85). In the Introduction, the third sentence of the second paragraph: For example, I PNPLA3 i p.I48M and I TM6SF2 i p.E40K, although initially identified as associated with hepatic steatosis [9,10], strongly predispose to the development of alcoholic cirrhosis [11], non-alcoholic cirrhosis [12,13] and hepatitis C-related cirrhosis [14,15]. should read: For example, I PNPLA3 i p.I1148M and I TM6SF2 i p.E167K, although initially identified as associated with hepatic steatosis [9,10], strongly predispose to the development of alcoholic cirrhosis [11], non-alcoholic cirrhosis [12,13] and hepatitis C-related cirrhosis [14,15].
- Subjects
LIVER diseases; GENES; MITOCHONDRIA
- Publication
PLoS Genetics, 2021, Vol 17, Issue 4, p1
- ISSN
1553-7390
- Publication type
Correction Notice
- DOI
10.1371/journal.pgen.1009503