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- Title
Genetic variation (population database) at 20 autosomal STR loci in the population of Rajasthan (north-western India).
- Authors
Kumar, Anand; Kumar, Rajesh; Kumawat, R. K.; Tilawat, Ajay; Shrivastava, Pankaj; Chaubey, Gyaneshwer
- Abstract
To explore the genetic diversity and establish the allelic database of the population of Rajasthan, we assessed 571 randomly selected unrelated healthy individuals residing in the state. Blood samples of the selected individuals were collected with the compliance of ethical standards. Locus Penta E was observed to be the most polymorphic (0.908), whereas locus TPOX was observed to be the least polymorphic (0.639). The observed heterozygosity ranged from a minimum of 0.667 (TPOX) to a maximum of 0.925 (Penta E). The combined value of the power of discrimination (PD) and power of exclusion (PE) for all the studied 20 short tandem repeat (STR) loci were observed to be 1 and 0.999999997560235 respectively. The combined values of matching probability (PM) and paternity index (PI) for all the studied 20 STR loci were 7 × 10−26 and 4 × 108 respectively. The obtained genetic data are useful for forensic DNA applications and expected to enrich the genetic database of Indian populations.
- Subjects
RAJASTHAN (India); FORENSIC genetics; MICROSATELLITE repeats; GENETIC databases; DATABASES
- Publication
International Journal of Legal Medicine, 2020, Vol 134, Issue 5, p1667
- ISSN
0937-9827
- Publication type
Article
- DOI
10.1007/s00414-020-02280-6