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- Title
InteractiveROSETTA: a graphical user interface for the PyRosetta protein modeling suite.
- Authors
Schenkelberg, Christian D.; Bystroff, Christopher
- Abstract
Modern biotechnical research is becoming increasingly reliant on computational structural modeling programs to develop novel solutions to scientific questions. Rosetta is one such protein modeling suite that has already demonstrated wide applicability to a number of diverse research projects. Unfortunately, Rosetta is largely a command-line-driven software package which restricts its use among non-computational researchers. Some graphical interfaces for Rosetta exist, but typically are not as sophisticated as commercial software. Here, we present InteractiveROSETTA, a graphical interface for the PyRosetta framework that presents easy-to-use controls for several of the most widely used Rosetta protocols alongside a sophisticated selection system utilizing PyMOL as a visualizer. InteractiveROSETTA is also capable of interacting with remote Rosetta servers, facilitating sophisticated protocols that are not accessible in PyRosetta or which require greater computational resources.
- Subjects
GRAPHICAL user interfaces; MEDICAL research; BIOINFORMATICS; STRUCTURAL bioinformatics; PROTEIN engineering; COMPUTER software
- Publication
Bioinformatics, 2015, Vol 31, Issue 24, p4023
- ISSN
1367-4803
- Publication type
Article
- DOI
10.1093/bioinformatics/btv492