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- Title
Palladium‐Catalyzed Intramolecular C−H Heteroarylation to Access Fused Tricyclic Oxazolo[4,5‐c]Quinolines.
- Authors
Kajol, Km; Kumar, Sujeet; Kumar, Amit; Kant, Ruchir; Ramesh, Chintakunta
- Abstract
Synthesis of fused tricyclic oxazolo[4,5‐c]quinolines from 2‐iodo‐N‐((2‐phenyloxazol‐4‐yl)methyl)anilines via intramolecular C−H heteroarylation in the presence of palladium catalyst under ligand free conditions has been disclosed. Various substituted 2‐iodo‐N‐((2‐phenyloxazol‐4‐yl)methyl)anilines are well tolerated and furnished the products in good yields. The synthetic utility of the resulting molecules has been demonstrated. This method features broad substrate scope, mild reaction conditions, good functional group tolerance, and scalability.
- Subjects
PALLADIUM catalysts; QUINOLINE; FUNCTIONAL groups; ANILINE
- Publication
Asian Journal of Organic Chemistry, 2022, Vol 11, Issue 4, p1
- ISSN
2193-5807
- Publication type
Article
- DOI
10.1002/ajoc.202200066