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- Title
Visible Light‐Induced Aerobic Oxidation of Indoles: One‐Pot Formation of 4‐Quinolones at Room Temperature.
- Authors
Ji, Xiaochen; Li, Dongdong; Wang, Zhongzhen; Tan, Muyun; Huang, Huawen; Deng, Guo‐Jun
- Abstract
Abstract: A one‐pot synthesis of 4‐quinolones starting from indoles is disclosed. This cascade reaction involves a photocatalytic aerobic oxidation of indoles using visible light and a subsequent base‐promoted Camps cyclization. The advantages of the present protocol include the use of environmentally benign and inexpensive oxygen as the sole oxidant, easy handling at room temperature, as well as step‐ and atom‐economy.
- Subjects
INDOLE compounds; QUINOLONE antibacterial agents
- Publication
Asian Journal of Organic Chemistry, 2018, Vol 7, Issue 4, p711
- ISSN
2193-5807
- Publication type
Article
- DOI
10.1002/ajoc.201800036