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Synthetic Molecules that Protect Cells from Anoikis and Their Use in Cell Transplantation.
Published in:
Angewandte Chemie International Edition, 2014, v. 53, n. 42, p. 11208, doi. 10.1002/anie.201405829
By:
- Frisco‐Cabanos, Heidie L.;
- Watanabe, Mizuki;
- Okumura, Naoki;
- Kusamori, Kosuke;
- Takemoto, Naohiro;
- Takaya, Junichiro;
- Sato, Shin‐ichi;
- Yamazoe, Sayumi;
- Takakura, Yoshinobu;
- Kinoshita, Shigeru;
- Nishikawa, Makiya;
- Koizumi, Noriko;
- Uesugi, Motonari
Publication type:
Article
Transcriptome dataset of human corneal endothelium based on ribosomal RNA-depleted RNA-Seq data.
Published in:
Scientific Data, 2020, v. 7, n. 1, p. 1, doi. 10.1038/s41597-020-00754-1
By:
- Tokuda, Yuichi;
- Okumura, Naoki;
- Komori, Yuya;
- Hanada, Naoya;
- Tashiro, Kei;
- Koizumi, Noriko;
- Nakano, Masakazu
Publication type:
Article
RNA-Seq–based transcriptome analysis of corneal endothelial cells derived from patients with Fuchs endothelial corneal dystrophy.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-35468-y
By:
- Nakagawa, Tatsuya;
- Tokuda, Yuichi;
- Nakano, Masakazu;
- Komori, Yuya;
- Hanada, Naoya;
- Tourtas, Theofilos;
- Schlötzer-Schrehardt, Ursula;
- Kruse, Friedrich;
- Tashiro, Kei;
- Koizumi, Noriko;
- Okumura, Naoki
Publication type:
Article
Corneal Endothelial Cell Fate Is Maintained by LGR5 Through the Regulation of Hedgehog and Wnt Pathway.
Published in:
Stem Cells, 2013, v. 31, n. 7, p. 1396, doi. 10.1002/stem.1390
By:
- Hirata-Tominaga, Kana;
- Nakamura, Takahiro;
- Okumura, Naoki;
- Kawasaki, Satoshi;
- Kay, Eunduck P.;
- Barrandon, Yann;
- Koizumi, Noriko;
- Kinoshita, Shigeru
Publication type:
Article
Synthetic Molecules that Protect Cells from Anoikis and Their Use in Cell Transplantation.
Published in:
Angewandte Chemie, 2014, v. 126, n. 42, p. 11390, doi. 10.1002/ange.201405829
By:
- Frisco ‐ Cabanos, Heidie L.;
- Watanabe, Mizuki;
- Okumura, Naoki;
- Kusamori, Kosuke;
- Takemoto, Naohiro;
- Takaya, Junichiro;
- Sato, Shin ‐ ichi;
- Yamazoe, Sayumi;
- Takakura, Yoshinobu;
- Kinoshita, Shigeru;
- Nishikawa, Makiya;
- Koizumi, Noriko;
- Uesugi, Motonari
Publication type:
Article
Rho kinase inhibitor enables cell-based therapy for corneal endothelial dysfunction.
Published in:
Scientific Reports, 2016, p. 26113, doi. 10.1038/srep26113
By:
- Okumura, Naoki;
- Sakamoto, Yuji;
- Fujii, Keita;
- Kitano, Junji;
- Nakano, Shinichiro;
- Tsujimoto, Yuki;
- Nakamura, Shin-ichiro;
- Ueno, Morio;
- Hagiya, Michio;
- Hamuro, Junji;
- Matsuyama, Akifumi;
- Suzuki, Shingo;
- Shiina, Takashi;
- Kinoshita, Shigeru;
- Koizumi, Noriko
Publication type:
Article
Density-gradient centrifugation enables the purification of cultured corneal endothelial cells for cell therapy by eliminating senescent cells.
Published in:
Scientific Reports, 2015, p. 1, doi. 10.1038/srep15005
By:
- Naoki Okumura;
- Ayaka Kusakabe;
- Hiroatsu Hirano;
- Ryota Inoue;
- Yugo Okazaki;
- Shinichiro Nakano;
- Shigeru Kinoshita;
- Noriko Koizumi
Publication type:
Article
Morphological Changes of Human Corneal Endothelial Cells after Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Administration: A Prospective Open-Label Clinical Study.
Published in:
PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0136802
By:
- Nakagawa, Hiroko;
- Koizumi, Noriko;
- Okumura, Naoki;
- Suganami, Hideki;
- Kinoshita, Shigeru
Publication type:
Article
Derivation of Mesenchymal Stromal Cells from Pluripotent Stem Cells through a Neural Crest Lineage using Small Molecule Compounds with Defined Media.
Published in:
PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0112291
By:
- Fukuta, Makoto;
- Nakai, Yoshinori;
- Kirino, Kosuke;
- Nakagawa, Masato;
- Sekiguchi, Kazuya;
- Nagata, Sanae;
- Matsumoto, Yoshihisa;
- Yamamoto, Takuya;
- Umeda, Katsutsugu;
- Heike, Toshio;
- Okumura, Naoki;
- Koizumi, Noriko;
- Sato, Takahiko;
- Nakahata, Tatsutoshi;
- Saito, Megumu;
- Otsuka, Takanobu;
- Kinoshita, Shigeru;
- Ueno, Morio;
- Ikeya, Makoto;
- Toguchida, Junya
Publication type:
Article
Cultivation of Corneal Endothelial Cells on a Pericellular Matrix Prepared from Human Decidua-Derived Mesenchymal Cells.
Published in:
PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088169
By:
- Numata, Ryohei;
- Okumura, Naoki;
- Nakahara, Makiko;
- Ueno, Morio;
- Kinoshita, Shigeru;
- Kanematsu, Daisuke;
- Kanemura, Yonehiro;
- Sasai, Yoshiki;
- Koizumi, Noriko
Publication type:
Article
Corneal Endothelial Expansion Promoted by Human Bone Marrow Mesenchymal Stem Cell-Derived Conditioned Medium.
Published in:
PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0069009
By:
- Nakahara, Makiko;
- Okumura, Naoki;
- Kay, EunDuck P.;
- Hagiya, Michio;
- Imagawa, Kiwamu;
- Hosoda, Yuuki;
- Kinoshita, Shigeru;
- Koizumi, Noriko
Publication type:
Article
Inhibition of TGF-β Signaling Enables Human Corneal Endothelial Cell Expansion <i>In Vitro</i> for Use in Regenerative Medicine.
Published in:
PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0058000
By:
- Okumura, Naoki;
- Kay, EunDuck P.;
- Nakahara, Makiko;
- Hamuro, Junji;
- Kinoshita, Shigeru;
- Koizumi, Noriko
Publication type:
Article
Ocular Surface Reconstruction With a Tissue-Engineered Nasal Mucosal Epithelial Cell Sheet for the Treatment of Severe Ocular Surface Diseases.
Published in:
Stem Cells Translational Medicine, 2015, v. 4, n. 1, p. 99, doi. 10.5966/sctm.2014-0169
By:
- KOBAYASHI, MASAKAZU;
- NAKAMURA, TAKAHIRO;
- YASUDA, MAKOTO;
- HATA, YUIKO;
- OKURA, SHOKI;
- IWAMOTO, MIYU;
- NAGATA, MAHO;
- FULLWOOD, NIGEL J.;
- KOIZUMI, NORIKO;
- HISA, YASUO;
- KINOSHITA, SHIGERU
Publication type:
Article
Guttae Morphology After Cultured Corneal Endothelial Cell Transplant in Fuchs Endothelial Corneal Dystrophy.
Published in:
JAMA Ophthalmology, 2024, v. 142, n. 9, p. 818, doi. 10.1001/jamaophthalmol.2024.2718
By:
- Tomioka, Yasufumi;
- Ueno, Morio;
- Yamamoto, Akihisa;
- Numa, Kohsaku;
- Tanaka, Hiroshi;
- Kitazawa, Koji;
- Toda, Munetoyo;
- Koizumi, Noriko;
- Tanaka, Motomu;
- Hamuro, Junji;
- Sotozono, Chie;
- Kinoshita, Shigeru
Publication type:
Article
Myogenic Differentiation from MYOGENIN-Mutated Human iPS Cells by CRISPR/Cas9.
Published in:
Stem Cells International, 2017, p. 1, doi. 10.1155/2017/9210494
By:
- Higashioka, Koki;
- Koizumi, Noriko;
- Sakurai, Hidetoshi;
- Sotozono, Chie;
- Sato, Takahiko
Publication type:
Article
Development of Poly Lactic/Glycolic Acid (PLGA) Microspheres for Controlled Release of Rho-Associated Kinase Inhibitor.
Published in:
Journal of Ophthalmology, 2017, p. 1, doi. 10.1155/2017/1598218
By:
- Koda, Sho;
- Okumura, Naoki;
- Kitano, Junji;
- Koizumi, Noriko;
- Tabata, Yasuhiko
Publication type:
Article
Application of Rho Kinase Inhibitors for the Treatment of Corneal Endothelial Diseases.
Published in:
Journal of Ophthalmology, 2017, p. 1, doi. 10.1155/2017/2646904
By:
- Okumura, Naoki;
- Kinoshita, Shigeru;
- Koizumi, Noriko
Publication type:
Article
U-Net Convolutional Neural Network for Real-Time Prediction of the Number of Cultured Corneal Endothelial Cells for Cellular Therapy.
Published in:
Bioengineering (Basel), 2024, v. 11, n. 1, p. 71, doi. 10.3390/bioengineering11010071
By:
- Okumura, Naoki;
- Nishikawa, Takeru;
- Imafuku, Chiaki;
- Matsuoka, Yuki;
- Miyawaki, Yuna;
- Kadowaki, Shinichi;
- Nakahara, Makiko;
- Matsuoka, Yasushi;
- Koizumi, Noriko
Publication type:
Article
Corneal endothelial cell therapy: feasibility of cell culture from corneas stored in organ culture.
Published in:
Cell & Tissue Banking, 2021, v. 22, n. 4, p. 551, doi. 10.1007/s10561-021-09918-8
By:
- He, Zhiguo;
- Okumura, Naoki;
- Sato, Masakazu;
- Komori, Yuya;
- Nakahara, Makiko;
- Gain, Philippe;
- Koizumi, Noriko;
- Thuret, Gilles
Publication type:
Article
Determining subclinical edema in fuchs endothelial corneal dystrophy: Scheimpflug versus anterior segment‐optical coherence tomography.
Published in:
Acta Ophthalmologica (1755375X), 2022, v. 100, p. N.PAG, doi. 10.1111/j.1755-3768.2022.0647
By:
- Cortez, Oliver Dorado;
- Crouzet, Emmanuel;
- Poinard, Sylvain;
- Gain, Philippe;
- Garcin, Thibaud;
- Okumura, Naoki;
- Koizumi, Noriko;
- Thuret, Gilles
Publication type:
Article
New potential markers for Fuchs corneal endothelial dystrophy: A proteomic study.
Published in:
Acta Ophthalmologica (1755375X), 2022, v. 100, p. N.PAG, doi. 10.1111/j.1755-3768.2022.0499
By:
- Aouimeur, Inès;
- Hanielle, Vaitinadapoule;
- Naoki, Okumura;
- Koizumi, Noriko;
- Gain, Philippe;
- Thuret, Gilles;
- He, Zhiguo
Publication type:
Article
Tissue engineered endothelial keratoplasty in rabbit: tips and tricks.
Published in:
Acta Ophthalmologica (1755375X), 2022, v. 100, n. 6, p. 690, doi. 10.1111/aos.15081
By:
- Crouzet, Emmanuel;
- He, Zhiguo;
- Ben Moussa, Olfa;
- Mentek, Marielle;
- Isard, Pierre‐Francois;
- Peyret, Benjamin;
- Forest, Fabien;
- Gain, Philippe;
- Koizumi, Noriko;
- Okumura, Naoki;
- Thuret, Gilles
Publication type:
Article
Study of TGFβ‐induced modifications in central and peripheral endothelium of normal corneas.
Published in:
Acta Ophthalmologica (1755375X), 2021, v. 99, p. N.PAG, doi. 10.1111/j.1755-3768.2020.0108
By:
- Aouimeur, Inès;
- Naoki, Okumura;
- Koizumi, Noriko;
- Gain, Philippe;
- Thuret, Gilles;
- He, Zhiguo
Publication type:
Article
Cultivated oral mucosal epithelial transplantation for persistent epithelial defect in severe ocular surface diseases with acute inflammatory activity.
Published in:
Acta Ophthalmologica (1755375X), 2014, v. 92, n. 6, p. e447, doi. 10.1111/aos.12397
By:
- Sotozono, Chie;
- Inatomi, Tsutomu;
- Nakamura, Takahiro;
- Koizumi, Noriko;
- Yokoi, Norihiko;
- Ueta, Mayumi;
- Matsuyama, Kotone;
- Kaneda, Hideaki;
- Fukushima, Masanori;
- Kinoshita, Shigeru
Publication type:
Article
Generation and Feasibility Assessment of a New Vehicle for Cell-Based Therapy for Treating Corneal Endothelial Dysfunction.
Published in:
PLoS ONE, 2016, v. 11, n. 6, p. 1, doi. 10.1371/journal.pone.0158427
By:
- Okumura, Naoki;
- Kakutani, Kazuya;
- Inoue, Ryota;
- Matsumoto, Daiki;
- Shimada, Tomoki;
- Nakahara, Makiko;
- Kiyanagi, Yumiko;
- Itoh, Takehiro;
- Koizumi, Noriko
Publication type:
Article
Gene expression and immunolocalisation of a calcium-activated chloride channel during the stratification of cultivated and developing corneal epithelium.
Published in:
Cell & Tissue Research, 2005, v. 323, n. 1, p. 177, doi. 10.1007/s00441-005-0059-2
By:
- Connon, Che J.;
- Kawasaki, Satoshi;
- Liles, Melody;
- Koizumi, Noriko;
- Yamasaki, Kenta;
- Nakamura, Takahiro;
- Quantock, Andrew J.;
- Kinoshita, Shigeru
Publication type:
Article
A Surgical Cryoprobe for Targeted Transcorneal Freezing and Endothelial Cell Removal.
Published in:
Journal of Ophthalmology, 2017, p. 1, doi. 10.1155/2017/5614089
By:
- Akhbanbetova, Alina;
- Nakano, Shinichiro;
- Littlechild, Stacy L.;
- Young, Robert D.;
- Zvirgzdina, Madara;
- Fullwood, Nigel J.;
- Weston, Ian;
- Weston, Philip;
- Kinoshita, Shigeru;
- Okumura, Naoki;
- Koizumi, Noriko;
- Quantock, Andrew J.
Publication type:
Article
Feasibility of a cryopreservation of cultured human corneal endothelial cells.
Published in:
PLoS ONE, 2019, v. 14, n. 6, p. 1, doi. 10.1371/journal.pone.0218431
By:
- Okumura, Naoki;
- Kagami, Takato;
- Watanabe, Kyoko;
- Kadoya, Saori;
- Sato, Masakazu;
- Koizumi, Noriko
Publication type:
Article
Crossover Randomized Study of Pharmacologic Effects of Ripasudil–Brimonidine Fixed-Dose Combination Versus Ripasudil or Brimonidine.
Published in:
Advances in Therapy, 2023, v. 40, n. 8, p. 3559, doi. 10.1007/s12325-023-02534-w
By:
- Tanihara, Hidenobu;
- Yamamoto, Tetsuya;
- Aihara, Makoto;
- Koizumi, Noriko;
- Minami, Hiroomi;
- Kojima, Satoshi;
- Isobe, Tomoyuki;
- Kanazawa, Mizuho;
- Suganami, Hideki;
- Owada, Yasuko;
- Mikami, Hiroshi;
- Yagi, Michio;
- Furuie, Hidetoshi;
- Hayashibara, Tomoko;
- Kawai, Eriko;
- Kano, Kiyoshi;
- Mashimo, Hisashi;
- Ando, Makoto;
- Takat, Masashi
Publication type:
Article
Long-term intraocular pressure-lowering efficacy and safety of ripasudil-brimonidine fixed-dose combination for glaucoma and ocular hypertension: a multicentre, open-label, phase 3 study.
Published in:
Graefe's Archive of Clinical & Experimental Ophthalmology, 2024, v. 262, n. 8, p. 2579, doi. 10.1007/s00417-024-06388-y
By:
- Tanihara, Hidenobu;
- Yamamoto, Tetsuya;
- Aihara, Makoto;
- Koizumi, Noriko;
- Fukushima, Atsuki;
- Kawakita, Koji;
- Kojima, Satoshi;
- Nakamura, Toka;
- Suganami, Hideki;
- Tagawa, Yoshitsugu;
- Watanabe, Hiroki;
- Shimizu, Kiyoshi;
- Iwasaki, Miki;
- Matsuzaki, Sakae;
- Ueda, Hiroko;
- Okayama, Ryoko;
- Matsuoka, Osamu;
- Hashida, Setsuko;
- Kobayashi, Sachi Amaki;
- Kiyosawa, Motohiro
Publication type:
Article
Wide-field contact specular microscopy analysis of corneal endothelium post trabeculectomy.
Published in:
Graefe's Archive of Clinical & Experimental Ophthalmology, 2018, v. 256, n. 4, p. 751, doi. 10.1007/s00417-017-3889-1
By:
- Okumura, Naoki;
- Matsumoto, Daiki;
- Okazaki, Yugo;
- Koizumi, Noriko;
- Sotozono, Chie;
- Kinoshita, Shigeru;
- Mori, Kazuhiko
Publication type:
Article
Stability, safety, and pharmacokinetics of ganciclovir eye drops prepared from ganciclovir for intravenous infusion.
Published in:
Japanese Journal of Ophthalmology, 2019, v. 63, n. 3, p. 289, doi. 10.1007/s10384-019-00665-8
By:
- Okumura, Naoki;
- Tanaka, Toshiyuki;
- Fukui, Yuya;
- Koizumi, Noriko
Publication type:
Article
Endothelial cell loss and graft survival after penetrating keratoplasty for laser iridotomy-induced bullous keratopathy.
Published in:
Japanese Journal of Ophthalmology, 2018, v. 62, n. 4, p. 438, doi. 10.1007/s10384-018-0598-1
By:
- Okumura, Naoki;
- Kusakabe, Ayaka;
- Koizumi, Noriko;
- Wakimasu, Koichi;
- Kayukawa, Kanae;
- Kondo, Masami;
- Mori, Kazuhiko;
- Sotozono, Chie;
- Kinoshita, Shigeru
Publication type:
Article
Shotgun proteomics identification of proteins expressed in the Descemet's membrane of patients with Fuchs endothelial corneal dystrophy.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-37104-1
By:
- Nakagawa, Tatsuya;
- Okumura, Naoki;
- Ikegawa, Masaya;
- Toyama, Yumiko;
- Nirasawa, Takashi;
- Mascarelli, Frederic;
- Vaitinadapoule, Hanielle;
- Aouimeur, Ines;
- He, Zhiguo;
- Gain, Philippe;
- Thuret, Gilles;
- Koizumi, Noriko
Publication type:
Article
Feasibility of cell-based therapy combined with descemetorhexis for treating Fuchs endothelial corneal dystrophy in rabbit model.
Published in:
PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0191306
By:
- Okumura, Naoki;
- Matsumoto, Daiki;
- Fukui, Yuya;
- Teramoto, Masataka;
- Imai, Hirofumi;
- Kurosawa, Tetta;
- Shimada, Tomoki;
- Kruse, Friedrich;
- Schlötzer-Schrehardt, Ursula;
- Kinoshita, Shigeru;
- Koizumi, Noriko
Publication type:
Article

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