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- Title
Nucleophilic ring-opening of epoxides: trends in β-substituted alcohols synthesis.
- Authors
Fallah-Mehrjardi, Mehdi; Kiasat, Ali Reza; Niknam, Khodabakhsh
- Abstract
The present review deals with the ring-opening of epoxides by various carbon, nitrogen, oxygen, halogen, and sulfur-containing nucleophiles, which most of the resulting products are versatile intermediates in the synthesis of various biologically active compounds. The regioselectivity and environmentally benign nature of procedures for the synthesis of similar products have been also discussed in detail.
- Subjects
NUCLEOPHILIC reactions; EPOXY compound derivatives; ALCOHOLS (Chemical class); BIOACTIVE compounds; HYDROLYSIS
- Publication
Journal of the Iranian Chemical Society, 2018, Vol 15, Issue 9, p2033
- ISSN
1735-207X
- Publication type
Article
- DOI
10.1007/s13738-018-1400-5