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- Title
Improvement in Hemodynamic Response Using a Quadripolar LV Lead.
- Authors
CABRERA BUENO, FERNANDO; ALZUETA RODRÍGUEZ, JAVIER; OLAGÜE DE ROS, JOSÉ; FERNÁNDEZ‐LOZANO, IGNACIO; GARCÍA GUERRERO, JUAN JOSÉ; DE LA CONCHA, JOAQUÍN FERNÁNDEZ; HERNÁNDEZ MADRID, ANTONIO; TOLOSANA VIU, JOSE MARÍA; OSCA ASENSI, JOAQUÍN; BARRERA CORDERO, ALBERTO; LLORENTE HERNANGÓMEZ, ELENA
- Abstract
Background The Quartet™ quadripolar lead (St. Jude Medical Inc., St. Paul, MN, USA) offers 10 different left ventricle pacing configurations that may further influence hemodynamic parameters compared to traditional bipolar pacing configurations. The purpose of this study was to evaluate whether pacing from additional quadripolar lead vectors could enhance cardiac output (CO). Methods For each patient, CO was measured in 'no-pacing' and in all the 10 configurations available, within 7 days of implantation of the device. Tip-ring, tip-right ventricular coil (RVC), and ring-RVC vectors were considered as traditional vectors. The seven additional configurations available in the quadripolar lead were considered as nontraditional vectors. CO was measured by ECHO. The best configuration was defined as the one presenting the highest CO measurement within configurations, which have a capture threshold <3 V and a safety margin between the capture and the phrenic nerve stimulation thresholds. Results Fifty-one standard cardiac resynchronization therapy patients were enrolled. The mean of each patient's best CO obtained with traditional vectors was higher than the baseline nonpaced CO (4.16 L/min vs 3.64 L/min). The mean of each patient's best CO, including all 10 available configurations, was also higher than the baseline nonpaced CO (4.33 L/min vs 3.64 L/min). In addition, the mean of each patient's best CO obtained with the best configuration available through a quadripolar lead was better than the mean of each patient's best CO obtained with a traditional configuration. In 53% of patients, the best CO was obtained with a nontraditional vector unique to the quadripolar lead. Conclusions A quadripolar lead offers multiple additional pacing options to increase CO acutely compared to conventional bipolar leads.
- Subjects
CARDIAC output; CARDIAC pacing; HEART ventricle diseases; ELECTROCARDIOGRAPHY; ELECTRODES; LEFT heart ventricle; ARTIFICIAL implants; HEART failure; LONGITUDINAL method; MEDICAL cooperation; HEALTH outcome assessment; PROBABILITY theory; RESEARCH; RESEARCH funding; PILOT projects; PRODUCT design; TREATMENT effectiveness; DATA analysis software; DESCRIPTIVE statistics; PREVENTION; DIAGNOSIS
- Publication
Pacing & Clinical Electrophysiology, 2013, Vol 36, Issue 8, p963
- ISSN
0147-8389
- Publication type
Article
- DOI
10.1111/pace.12172