We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Targeting a new regulator of erythropoiesis to alleviate anemia.
- Authors
Paulson, Robert F
- Abstract
The article discusses the studies that aim at identifying the complications caused by ineffective erythropoiesis in the diseased condition of anemia. The topics discussed include identifying the role of Growth differentiation factor 11 (GDF11) in regulating erythropoiesis, and effect of inhibition of GDF11 in mouse models of anemia with ineffective erythropoiesis in restoring normal erythropoietic differentiation and alleviating anemia, and oxidative stress caused by complications.
- Subjects
ERYTHROPOIETIC failure; GROWTH factors; ANEMIA; ANIMAL models in research; ANEMIA treatment; OXIDATIVE stress
- Publication
Nature Medicine, 2014, Vol 20, Issue 4, p334
- ISSN
1078-8956
- Publication type
Article
- DOI
10.1038/nm.3524